O. Sporns

Publications390
h-index102
Citations71,780
Highly Influential Citations3,681
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Complex network measures of brain connectivity: Uses and interpretations
TLDR
Construction of brain networks from connectivity data is discussed and the most commonly used network measures of structural and functional connectivity are described, which variously detect functional integration and segregation, quantify centrality of individual brain regions or pathways, and test resilience of networks to insult.
Mapping the Structural Core of Human Cerebral Cortex
TLDR
The spatial and topological centrality of the core within cortex suggests an important role in functional integration and a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants.
Complex brain networks: graph theoretical analysis of structural and functional systems
TLDR
This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
Complex brain networks: graph theoretical analysis of structural and functional systems
Rich-Club Organization of the Human Connectome
TLDR
It is demonstrated that brain hubs form a so-called “rich club,” characterized by a tendency for high-degree nodes to be more densely connected among themselves than nodes of a lower degree, providing important information on the higher-level topology of the brain network.
The economy of brain network organization
TLDR
It is proposed that brain organization is shaped by an economic trade-off between minimizing costs and allowing the emergence of adaptively valuable topological patterns of anatomical or functional connectivity between multiple neuronal populations.
Predicting human resting-state functional connectivity from structural connectivity
TLDR
Although resting state functional connectivity is variable and is frequently present between regions without direct structural linkage, its strength, persistence, and spatial statistics are nevertheless constrained by the large-scale anatomical structure of the human cerebral cortex.
Networks of the Brain
Over the last decade, the study of complex networks has expanded across diverse scientific fields. Increasingly, science is concerned with the structure, behavior, and evolution of complex systems…
The Human Connectome: A Structural Description of the Human Brain
TLDR
A research strategy to achieve the connection matrix of the human brain (the human “connectome”) is proposed, and its potential impact is discussed.
Network structure of cerebral cortex shapes functional connectivity on multiple time scales
TLDR
Simulating nonlinear neuronal dynamics on a network that captures the large-scale interregional connections of macaque neocortex, and applying information theoretic measures to identify functional networks, this work finds structure–function relations at multiple temporal scales.
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