O. Simonova

Publications78
h-index7
Citations546
Highly Influential Citations59
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A drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation
The suppressor of Hairy wing (su(Hw)) protein inhibits the function of transcriptional enhancers located distally from the promoter with respect to the location of su(Hw)-binding sites. This polarity… Expand
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Two Isoforms of Drosophila TRF2 Are Involved in Embryonic Development, Premeiotic Chromatin Condensation, and Proper Differentiation of Germ Cells of Both Sexes
ABSTRACT The Drosophila TATA box-binding protein (TBP)-related factor 2 (TRF2 or TLF) was shown to control a subset of genes different from that controlled by TBP. Here, we have investigated the… Expand
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A novel transposition system in Drosophila melanogaster depending on the Stalker mobile genetic element.
Crosses between the Drosophila melanogaster y2sc1waG strain or some of its derivatives and the FM4 strain yielded insertional mutagenesis with a frequency of 10(‐3)‐10(‐4). The system differs in… Expand
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Combination of Hypomorphic Mutations of the Drosophila Homologues of Aryl Hydrocarbon Receptor and Nucleosome Assembly Protein Family Genes Disrupts Morphogenesis, Memory and Detoxification
Aryl hydrocarbon receptor is essential for biological responses to endogenous and exogenous toxins in mammals. Its Drosophila homolog spineless plays an important role in fly morphogenesis. We have… Expand
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Cerd4, third member of the d4 gene family: expression and organization of genomic locus
Abstract. Two members of the d4 family of presumptive transcription modulators, neuro-d4 (Neud4) and ubi-d4/Requiem (Req), have been characterized previously. We cloned and characterized the third… Expand
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Expression pattern of dd4, a sole member of the d4 family of transcription factors in Drosophila melanogaster
In vertebrates, three members of the d4 gene family code for proteins, which are believed to function as transcription factors and involved in regulation of various intracellular processes. One… Expand
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[D4 family genes in vertebrates: genomic organization and expression].
A family of closely related genes, named the d4 family, has been previously identified in mammals. It comprises three genes encoding structurally related proteins. The hallmark of the family is d4… Expand
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Morphogenetic movement of cells in embryogenesis of Drosophila melanogaster: Mechanism and genetic control
Morphogenetic movement of cells is of significant importance in embryogenesis. It is necessary to identify the final position and configuration of the embryo’s tissues and share the positional… Expand
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Changes in the physiological and pathological EEG activity of epilepsies during mental activity and awareness
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Xenobiotic-induced activation of human aryl hydrocarbon receptor target genes in Drosophila is mediated by the epigenetic chromatin modifiers
Aryl hydrocarbon receptor (AHR) is the key transcription factor that controls animal development and various adaptive processes. The AHR’s target genes are involved in biodegradation of endogenous… Expand
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