O. Shimomura

Publications531
h-index63
Citations16,070
Highly Influential Citations465
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Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea.
Bioluminescence: Chemical Principles and Methods
In-situ measurement of viscosity and density of carbonate melts at high pressure
In situ observation of the olivine‐spinel phase transformation in Fe2SiO4 using synchrotron radiation
Detailed in situ observations of the olivine-spinel phase transformation in Fe2SiO4 were performed using a cubic anvil type of high-pressure and high-temperature X ray diffraction apparatus combined…
The Phase Boundary Between α- and β-Mg2SiO4 Determined by in Situ X-ray Observation
The stability of Mg2SiO4, a major constituent in the Earth's mantle, has been investigated experimentally by in situ observation with synchrotron radiation. A cubic-type high-pressure apparatus…
Phase relations of CaCO3 at high pressure and high temperature
Abstract Phase transitions in calcite, a naturally occurring crystalline form of CaCO3, have been investigated by three different experimental techniques: (1) in-situ X-ray diffraction (XRD) using…
The crystal structure of the photoprotein aequorin at 2.3 Å resolution
TLDR
The structure of recombinant aequorin is found to be a globular molecule containing a hydrophobic core cavity that accommodates the ligand coelenterazine-2-hydroperoxide and suggests a mechanism by which calcium activation may occur.
BIOLUMINESCENCE
The present review covers approximately 150 papers that were published in 1982 and the first half of 1983 or are in press. In the last several years, there has been a steady increase in the number of…
Intermolecular energy transfer in the bioluminescent system of Aequorea.
TLDR
In the present study, GFP has been purified, crystallized, and partially characterized and an energy transfer in citro from aequorin to this protein has been demonstrated.
The discovery of aequorin and green fluorescent protein
TLDR
In the characterization of these proteins, information obtained from the bioluminescence of the ostracod Cypridina played an extremely important role, and without the information gained on CyPRidina luminescence, the characterize of aequorin would not have been possible.
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