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Hepatocellular carcinoma in Egypt: a single center study over a decade.
TLDR
There was nearly a twofold increase of the proportion of HCC among CLD patients in Egypt with a significant decline of HBV and slight increase of HCV as risk factors over a decade, and Alpha-fetoprotein played a limited role in diagnosis. Expand
Prevalence and epidemiological features of hepatocellular carcinoma in Egypt-a single center experience.
TLDR
HCC is showing an increasing trend among patients and its development is mainly due to high rates of HCVAb and HBsAg positivity, which renders its contribution to the development of HCC over seven-fold higher than HBs Ag positivity. Expand
Response of Hepatitis C Genotype-4 Naïve Patients to 24 Weeks of Peg-Interferon-α2b/Ribavirin or Induction-Dose Interferon-α2b/Ribavirin/Amantadine: A Non-Randomized Controlled Study
TLDR
Response of genotype-4 patients to 24 wks of Peg-IFN-α2b/RBV did not significantly differ from 48 wks, but was significantly higher than IDTT, which may indicate that genotype 4 is “not difficult to treat” as previously reported. Expand
Association of chronic hepatitis C infection and diabetes mellitus.
TLDR
Chronic hepatitis C patients in Egypt are three times more likely to develop DM than HCV seronegative patients, and pancreatic beta -cells might be an extrahepatic target of HCV. Expand
Prevalence of GBV-C/hepatitis G virus viraemia among blood donors, health care personnel, chronic non-B non-C hepatitis, chronic hepatitis C and hemodialysis patients in Egypt.
TLDR
It is concluded that there is a relatively high prevalence of GBV-C/HGV-RNA among different Egyptian groups compared to international figures and the main risk factors were direct percutaneous exposure rather than blood transfusion. Expand
Non‐interferon‐based therapy: an option for amelioration of necro‐inflammation in hepatitis C patients who cannot afford interferon therapy
TLDR
The aim was to tailor an effective and inexpensive regimen that ameliorates hepatic necro‐inflammatory activity among chronic hepatitis C patients. Expand
Bile duct carcinoma in Egypt: possible etiological factors.
TLDR
There might be an association between chronic fecal typhoid carrier state and bile duct carcinoma, according to statistical analysis of the results. Expand
Does schistosomiasis play a role in the high sero prevalence of HCV antibody among Egyptians?
TLDR
It is concluded that HCV antibodies were significantly higher in schistosomal antibody positive Egyptians, there was no cross reactivity between the two antibodies and the high prevalence could be due to HCV transmission during anti-bilharzial parenteral therapy or due to depressed cell mediated immunity associated with schistsosomal infection. Expand
Prevalence of delta antibodies among urban HBsAg-positive chronic liver disease patients in Egypt.
TLDR
The prevalence of delta infection among urban Egyptians is reported for the first time and points to a high prevalence of hepatitis delta virus in Egypt. Expand
Hepatitis C virus genotypes among HCV-chronic liver disease patients in Egypt: a leading trial.
TLDR
It appears that Egypt hosts predominantly HCV genotype 4 and less commonly genotype 1, which might have important implications concerning the epidemiological aspects, pathogenesis and response to antiviral therapy. Expand
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