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Experimental anti-alveolar basement membrane antibody-mediated pneumonitis. I. The role of increased permeability of the alveolar capillary wall induced by oxygen.
Attempts to produce in animals lung lesions mediated by anti-alveolar basement membrane (ABM) antibodies have thus far been inconclusive. The aim of the present study was to test the hypothesis thatExpand
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Liver arginase. III. Properties of highly purified arginase.
Abstract 1. 1. Arginase has been prepared from horse liver which exhibited one major component and a minor, slower-moving component upon electrophoresis at pH 7.35. Ultracentrifugal analysis alsoExpand
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Specific Binding Activity of Isolated Light Chains of Antibodies
Free light chains isolated from specifically purified antibody have been shown to bind specific hapten. This proves that part of the binding site does exist on the light chain. The light chains wereExpand
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[35] Iodination-Isolation of peptides from the active site.
Publisher Summary This chapter presents that for iodinating a protein, several reagents or combinations of reagents, including triiodide ion, iodine monochloride, iodine in alcohol, and iodide ionExpand
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Liver arginase. IV. Effect of pH on kinetics of manganese-activated enzyme.
Abstract 1. 1. The pH-activity curve of purified Mn++-activated arginase, virtually free of other activating cations has been determined. The curve shows the optimum activity to be at pH 10.2. TheExpand
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Amino acid sequence of the light chain derived from a rabbit anti-p-azobenzoate antibody of restricted heterogeneity.
Abstract The amino acid sequence of the light chain from a specifically purified rabbit (No. 2717) anti- p -azobenzoate antibody preparation (b4 allotype) of restricted heterogeneity has beenExpand
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SPECIFIC COMBINATION OF H AND L CHAINS OF RABBIT GAMMA-GLOBULINS.
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Antibodies of limited heterogeneity: L chains of a single mobility.
Abstract The specifically purified anti-p-azobenzoate antibody from two rabbits (out of nine rabbits that had been injected with a heterogensous antigen (azo-p-benzoate-bovine-γ-globulin conjugate))Expand
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CHEMICAL AND STRUCTURAL DIFFERENCES BETWEEN ANTIBODIES CAPABLE OF BINDING A PARTICULAR HAPTEN GROUP: EVIDENCE FOR LIMITED HETEROGENEITY *
In recent years, information has been forthcoming about the chemical nature of the combining regions of antibody molecules, i.e., the contact amino acids in the combining region. Nearly all suchExpand
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