Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
l‐α‐Lysophosphatidylinositol (LPI) aggravates myocardial ischemia/reperfusion injury via a GPR55/ROCK‐dependent pathway
- O. Robertson-Gray, S. Walsh, E. Ryberg, A. Jönsson-Rylander, C. Lipina, C. Wainwright
- Biology, ChemistryPharmacology research & perspectives
- 24 May 2019
Raised levels of LPI in the vicinity of a developing infarct may worsen the outcome of AMI, and activation of the Rho kinase/ROCK/p38 MAPK pathway is responsible for LPI‐induced extension of I/R injury.
Cyclophilin D palmitoylation and permeability transition: a new twist in the tale of myocardial ischaemia-reperfusion injury.
Studies on the role of GPR55 in cardiovascular physiology and pathophysiology
- O. Robertson-Gray
- Biology, Medicine
- 1 December 2017
Evidence is provided that GPR 55 may have the potential to be targeted for therapeutic gains in atherosclerosis and myocardial I/R injury and the signalling mechanisms by which GPR55 elicits any observed effects on the myocardium in response to such injury.