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Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
This report describes the behavioral and electrophysiological analysis of regulatable transgenic mice expressing mutant repeat domains of human Tau (TauRD). Mice were generated to express TauRD inExpand
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The lichen genus Usnea in East Fennoscandia. III. The shrubby species
Nine shrubby Usnea species are reported from East Fennoscandia: Usnea diplotypus Vain., U. fulvoreagens (Räsänen) Räsänen, U. glabrata (Ach.) Vain., U. glabrescens (Nyl. ex Vain.) Vain. ex Räsänen,Expand
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Age-dependent neuroinflammation and cognitive decline in a novel Ala152Thr-Tau transgenic mouse model of PSP and AD
IntroductionMutations of Tau are associated with several neurodegenerative disorders. Recently, the Tau mutation A152T was described as a novel risk factor for frontotemporal dementia spectrumExpand
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Soot and NO formation in methane-oxygen enriched diffusion flames
NO and soot formation were investigated both numerically and experimentally in oxygen-enriched counterflow diffusion flames. Two sets of experiments were conducted. In the first set, the soot volumeExpand
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Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
IntroductionNeurofibrillary tangles (NFT) composed of Tau are hallmarks of neurodegeneration in Alzheimer disease. Transgenic mice expressing full-length pro-aggregant human Tau (2N4R Tau-ΔK280,Expand
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Magnetic phase transitions in nanostructures with different cluster orderings
Nanostructures have been synthesized by (i) the micellar template method with the subsequent organization of Fe2O3 nanoclusters about 10 nm in size to a cluster crystal and (ii) by the aerosol methodExpand
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[ANALYSIS OF POPULATION IMMUNITYAGAINST INFLUENZA PRIOR TO 2014 AND 2015 EPIDEMIC SEASONS].
AIM Control for the population herd immunity against seasonal influenza viruses as well as for emergence of antibodies against influenza with pandemic potential in human blood sera. MATERIALS ANDExpand
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Synthesis of Functionalized 2-(2-Pyrrolyl)pyrazolo[1,5-a]pyrimidines
Reactions of 5-amino-3-(2-pyrrolyl)pyrazoles with β-dicarbonyl compounds (acetylacetone and ethyl acetoacetate) lead to formation of up to 90% of polysubstituted pyrazolo[1,5-a]pyrimidines.
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General route to symmetric and asymmetric meso-CF3-3(5)-aryl(hetaryl)- and 3,5-diaryl(dihetaryl)-BODIPY dyes.
A general efficient route to hitherto inaccessible symmetric and asymmetric meso-CF(3)-BODIPY dyes has been developed. The key stages include the reduction of available 2-trifluoroacetylpyrroles toExpand
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C—H···X (X = N, O, S) intramolecular interaction in 1‐vinyl‐2‐(2′‐heteroaryl)pyrroles as monitored by 1H and 13C NMR spectroscopy
1H and 13C NMR spectroscopy of a series of 1‐vinyl‐2‐(2′‐heteroaryl)‐pyrroles were employed for the analysis of their electronic and spatial structure. The C—H···N intramolecular interaction betweenExpand
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