• Publications
  • Influence
NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer
The transcription factor nuclear factor kappa B (NF-κB) and the long non-coding RNA (lncRNA) HOTAIR (HOX transcript antisense RNA) have diverse functional roles in cancer. In this study, we show thatExpand
  • 130
  • 2
Protein kinase A-mediated Phosphorylation Regulates STAT3 Activation and Oncogenic EZH2 Activity
Polycomb repressive complex 2 (PRC2) member enhancer of zeste homolog 2 (EZH2) trimethylates histone H3 lysine 27 (H3K27me3), alters chromatin structure and contributes to epigenetic regulation ofExpand
  • 10
AKT-mediated phosphorylation of TWIST1 is essential for breast cancer cell metastasis
Previously, it was shown that human TWIST1 (basic helix-loop-helix (b-HLH) is phosphorylated by Akt kinase at S42, T121, and S123. To show in vivo effect of these phosphorylations, we created mouseExpand