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Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma: A Paradigm Shift to Reduce Overtreatment of Indolent Tumors.
TLDR
Thyroid tumors currently diagnosed as noninvasive EFVPTC have a very low risk of adverse outcome and should be termed NIFTP, and this reclassification will affect a large population of patients worldwide and result in a significant reduction in psychological and clinical consequences associated with the diagnosis of cancer. Expand
Spindle Cell Oncocytomas and Granular Cell Tumors of the Pituitary Are Variants of Pituicytoma
TLDR
Diffuse TTF-1 expression in nontumorouspituicytes, pituicytomas, spindle cell oncocytoma, and granular cell tumors indicates a common pitUicyte lineage. Expand
The Complementary Role of Transcription Factors in the Accurate Diagnosis of Clinically Nonfunctioning Pituitary Adenomas
TLDR
The results justify the complementary role of transcription factors in the precise classification of NFAs that can more accurately characterize biological behavior and suggest that more than one quarter of hormone-negative adenomas are SCAs that share distinct clinicopathological features with ACTH-expressing SCAs. Expand
Overview of the 2017 WHO Classification of Pituitary Tumors
This review focuses on discussing the main changes on the upcoming fourth edition of the WHO Classification of Tumors of the Pituitary Gland emphasizing histopathological and molecular geneticsExpand
Pathological definition and clinical significance of vascular invasion in thyroid carcinomas of follicular epithelial derivation
TLDR
It is suggested that the criteria for diagnosing angioinvasion in thyroid carcinomas as well as in other endocrine tumors are inconsistent and the controversy may be attributed to application of inappropriate criteria. Expand
Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.
TLDR
Integrated subtype analysis identified three ACC subtypes with distinct clinical outcome and molecular alterations which could be captured by a 68-CpG probe DNA-methylation signature, proposing a strategy for clinical stratification of patients based on molecular markers. Expand
Biomarkers of aggressive pituitary adenomas.
TLDR
Evidence suggests that the additional analyses of FGFR4, MMP, PTTG, Ki-67, p53, and deletions in chromosome 11 may contribute to decisions concerning management of aggressive pituitary adenomas. Expand
Clinicopathological Correlations in Pituitary Adenomas
TLDR
The clinical responsibility of pathologists is not only limited to the distinction of pituitary adenomas from other sellar lesions, but also to provide a comprehensive subtype classification using appropriate ancillary tools. Expand
Epithelioid angiomyolipoma: a morphologically distinct variant that mimics a variety of intra-abdominal neoplasms.
This review examines the histopathologic, immunohistochemical, ultrastructural, and molecular biologic features of epithelioid angiomyolipoma (EAML), with an emphasis on the differential diagnosis ofExpand
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