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Contribution to characterization of oxidative stress in HIV/AIDS patients.
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Ozone oxidative preconditioning: a protection against cellular damage by free radicals.
TLDR
These are the first experimental results showing that repeated administration of ozone in atoxic doses is able to induce an adaptation to oxidative stress thus enabling the animals to maintain hepatocellular integrity after CCl4 poisoning.
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Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils
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Similar protective effect of ischaemic and ozone oxidative preconditionings in liver ischaemia/reperfusion injury.
TLDR
Evidence is provided that both of the preconditioning settings share similar biochemical mechanisms of protection in the parameters which were measured and the histological results showed a more effective protection of OzoneOP than IscheP in the authors' experimental conditions.
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Assessment of the relative contribution of COX‐1 and COX‐2 isoforms to ischemia‐induced oxidative damage and neurodegeneration following transient global cerebral ischemia
TLDR
These results provide the first evidence that both COX isoforms are involved in the progression of neuronal damage following global cerebral ischemia, and have important implications for the potential therapeutic use of COX inhibitors in cerebral is chemia.
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Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils
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Protective effect of ozone treatment on the injury associated with hepatic ischemia-reperfusion: antioxidant-prooxidant balance.
TLDR
A protective effect of ozone treatment is reported on the injury associated to hepatic I/R, related to its action on endogenous antioxidants and prooxidants balance in favour of antioxidants, thus attenuating oxidative stress.
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Ozone therapy: clinical and basic evidence of its therapeutic potential.
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Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats.
TLDR
The results show that repeated administration of ozone in non-toxic doses might play a role in the control of diabetes and its complications and promote an oxidative preconditioning or adaptation to oxidative stress, preventing the damage induced by reactive oxygen species (ROS).
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Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats
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