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A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus
TLDR
It is concluded that, depending on membrane voltage, about one‐fifth to one‐quarter of the EPSC generated by the excitatory synaptic input to the hippocampal CA1 neurons of rat is due to the activity of P2X receptors.
The ASICs: Signaling molecules? Modulators?
  • O. Krishtal
  • Biology
    Trends in Neurosciences
  • 1 September 2003
Role for P2X Receptors in Long-Term Potentiation
TLDR
It is suggested that, by controlling the background calcium and thus the activity of NMDA receptors at low firing frequencies, P2X receptors act as a dynamic low-frequency filter so that weak stimuli do not induce LTP.
Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape ‘superslow’ afterburst EPSC in rat hippocampus
TLDR
Long‐term potentiation (LTP) induced by successive rounds of burst stimulation is accompanied by a long‐term increase in the contribution of extrasynaptic receptors in the afterburst EPSCNMDA.
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