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Bracelet protein: a quaternary structure proposed for the giant extracellular hemoglobin of Lumbricus terrestris.
A model is proposed in which it is postulated that the stoichiometries of some of the subunits need not be constant and that subunits D1 and D2 either form a "bracelet" decorated with complexes of T and M subunits or serve as "linkers" between the latter, to provide the appearance of a two-tiered hexagonal structure. Expand
Alignment of 700 globin sequences: Extent of amino acid substitution and its correlation with variation in volume
A continuum of amino acid sequences able to assume the common three‐on‐three α‐helical structure is implied and it is suggested that the determinants of the latter include sites other than those inaccessible to solvent. Expand
Adventitious variability? The amino acid sequences of nonvertebrate globins.
A number of the one-, two- and multi-domain globin chains participate in a broad variety of quaternary structures, ranging from homo- and heterodimers to highly complex, multisubunit aggregates with M(r) > 3000 kDa. Expand
Removal of sodium dodecyl sulfate from proteins.
Effective removal of sodium dodecyl sulfate from proteins in water or sodium phosphate buffer was achieved by column chromatography using the ion-retardation resin AG11A8. An average recovery of 83%Expand
Scanning transmission electron microscopy of extracellular annelid hemoglobins
Micrographs of negatively stained extracellular hemoglobins of Lumbricus terrestris and Arenicola marina obtained with the scanning transmission electron microscope show that their appearance isExpand
The reassociation of Lumbricus terrestris hemoglobin dissociated at alkaline pH.
The results suggest that reassociation comprises two pathways: one leading to the formation of IaR and a "dead-end" pathway, along which reassociation stops at the level of Ib. Expand
Comparison of the molecular size and shape of the extracellular hemoglobins of tubifex tubifex and lumbricus terrestris
Comparison of the morphologies of the two hemoglobins by examination of individual pixel lines through their digital projections suggests that the molecules are very similar in overall structure. Expand
Structure and Function of Invertebrate Oxygen Carriers
This book, based on a Symposium at the 10th International Biophysics Congress in 1990, provides a synthesis of recent advances in knowledge of invertebrate oxygen carriers such as haemoglobins, haemocyanins and haemorythrins. Expand
The dissociation of Lumbricus terrestris hemoglobin: a model of its subunit structure.
A model of the subunit structure of the hemoglobin is proposed which accounts for the known properties of this molecule and the subunits observed upon its dissociation. Expand
The dissociation of annelid extracellular hemoglobins and their quaternary structure
Abstract The recent measurements of the molecular mass and size of the annelid extracellular hemoglobins and studies of their dissociation in the presence of sodium dodecyl sulfate (SDS) and atExpand