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SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope
TLDR
It is demonstrated that the GAL locus is subject to sub-diffusive movement, which after activation can become constrained to a two-dimensional sliding motion along the nuclear envelope, which is in accordance with the ‘gene gating’ hypothesis.
Nuclear Export of 60S Ribosomal Subunits Depends on Xpo1p and Requires a Nuclear Export Sequence-Containing Factor, Nmd3p, That Associates with the Large Subunit Protein Rpl10p
TLDR
It is concluded that nuclear export of 60S subunits requires the nuclear export sequence-containing nonribosomal protein Nmd3p, which directly binds to the large subunit protein Rpl10p.
A Noc Complex Specifically Involved in the Formation and Nuclear Export of Ribosomal 40 S Subunits*
TLDR
Noc4p and Nop14p form a novel Noc complex with a specific role in nucleolar 40 S subunit formation and subsequent export to the cytoplasm.
High-resolution statistical mapping reveals gene territories in live yeast
TLDR
A computational imaging approach that creates high-resolution probabilistic maps of subnuclear domains occupied by individual loci in budding yeast through automated analysis of thousands of living cells is developed and found that genomic loci are confined to 'gene territories' much smaller than the nucleus.
High-throughput chromatin motion tracking in living yeast reveals the flexibility of the fiber throughout the genome.
TLDR
The analysis of the amplitude of fluctuations by the Rouse model shows that yeast chromatin is highly flexible, its persistence length being qualitatively estimated to <30 nm and suggesting that it provides a consistent framework to study chromatin dynamics.
Hmo1, an HMG‐box protein, belongs to the yeast ribosomal DNA transcription system
TLDR
Hmo1 overexpression suppresses rpa49‐Δ mutants lacking Rpa49, a non‐essential but conserved subunit of RNA polymerase I corresponding to the animal RNA polymerases I factor PAF53, and strongly increases de novo rRNA synthesis.
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