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Anxiolytic-like effect of chronic treatment with Erythrina velutina extract in the elevated plus-maze test.
Chronic administration of the hydroalcoholic extract of the stem bark of Erythrina velutina exerts an anxiolytic-like effect on mice, and it could serve as a new approach for the treatment anxiety, although it may have an amnesic effect at low doses. Expand
Involvement of monoaminergic system in the antidepressant-like effect of the hydroalcoholic extract of Siphocampylus verticillatus.
The biochemical data show that the extract of S. verticillatus elicited a significant antidepressant-like effect, when assessed in the TST and FST in mice, which seems to involve an interaction with adrenergic, dopaminergic, glutamatergic and serotonergic systems. Expand
Chemical and preliminary analgesic evaluation of geraniin and furosin isolated from Phyllanthus sellowianus.
Data extend previous studies and indicate that the two ellagitannins isolated from P.sellowianus, identified as furosin and geraniin are, at least in part, responsible for the antinociceptive actions reported previously for the hydroalcoholic extract of P. sellowianu and other plants belonging to the genus Phyllanthus. Expand
Genotoxicity of Achillea millefolium essential oil in diploid cells of Aspergillus nidulans
The genotoxicity of the oil was associated with the induction of mitotic non‐disjunction or crossing‐over by oil, and the genotoxic activity of A. millefolium oil was demonstrated to exert an in vitro antimicrobial activity against human pathogens. Expand
Antinociceptive properties of the new alkaloid, cis-8, 10-di-N-propyllobelidiol hydrochloride dihydrate isolated from Siphocampylus verticillatus: evidence for the mechanism of action.
DPHD produces dose-dependent and pronounced systemic, spinal, and supraspinal antinociception in mice, including against the neurogenic nocICEption induced by formalin and capsaicin. Expand
Antinociceptive properties of extracts of new species of plants of the genus Phyllanthus (Euphorbiaceae).
Results of the present study extend previous data and indicate that all extracts of Phyllanthus plants so far studied exhibit pronounced antinociceptive when assessed in chemical models of nociception, namely acetic acid-induced writhing, and formalin and capsaicin-induced licking. Expand
The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester.
GAEE produces dose-dependent and pronounced systemic, spinal and supraspinal antinociception in mice, probably via activation of K + channels and by a Gi/o pertussis toxin-sensitive mechanism. Expand
Anti-Helicobacter pylori activity of plant extracts traditionally used for the treatment of gastrointestinal disorders
The results presented in this work demonstrated that among the plant preparations analyzed, B. orellana L., C. recutita L., I. paraguariensis A. St.-Hil. Expand
Evaluation of larvicidal activity and ecotoxicity of linalool, methyl cinnamate and methyl cinnamate/linalool in combination against Aedes aegypti.
The results showed that, despite the higher larvicidal activity of methyl cinnamate, the use of MC-L as a larvicide seems to be more appropriate due to its significant larv suicidal activity and low toxicity. Expand
Phytochemical and antibacterial evaluation of essential oils from Ottonia martiana miq. (Piperaceae)
Three essential oils extracted from leaves, fruits and roots of Ottonia martiana Miq. (Piperaceae), common species in Brazilian Rain Forest, known as "anestesia", were analyzed by GC-MS and tested inExpand