Information System for Monitoring the Movement of Medicines as a Means of Increasing the Effectiveness of Pharmacovigilance
- O. Filippova, S. V. Greibo, N. Pronkin
- 5 May 2020
The article formulates the main possibilities of using a monitoring system for the needs of pharmacovigilance, and the alleged causes of the appearance of undesirable effects during the use of medicines and the features of their identification are determined.
Azacycloalkanes. XXXIV. Synthesis and Antiarrhythmic Activity of 2-(2′-R-2′-Hydroxyethyl)-1,2,3,4-tetra-hydro-pyrrolo-[1,2-a]pyrazines
- A. M. Likhosherstov, O. Filippova, K. Reznikov
- ChemistryPharmaceutical Chemistry Journal
- 10 June 2003
Previously, it was demonstrated that many piperazine derivatives possess antiarrhythmic properties [1, 2]. Here we report on the synthesis and antiarrhythmic activity of a series of 2-[(2 -hydroxy-2…
Clinical and morphological characteristics of the vascular bed of hypertrophic scar tissue in different periods of its formation
- O. Filippova, Филиппова Ольга Васильевна, Вашетко Ростислав Вадимович
- 9 October 2017
The vascular cross sectional area in the early stages of scar formation is attributable to the expansion of their lumen vessels, and the use of a hypertrophic scar for the creation of rotational and other flaps is associated with a high risk of trophic complications.
Ultrasonic dopplerography for the evaluation of endothelial function in the conduct of pharmacological vascular samples in an experiment
- V. Soldatov, T. Malorodova, O. Filippova
- Medicine, Biology
- 13 August 2018
To study the function of the endothelium in conducting vascular pharmacological samples in normal and blocking the synthesis of nitric oxide by ultrasound examination of the velocity of central blood…
Shape Memory Polymers as Smart Materials: A Review
- T. Dayyoub, A. Maksimkin, O. Filippova, V. Tcherdyntsev, D. Telyshev
- Materials SciencePolymers
- 26 August 2022
Polymer smart materials are a broad class of polymeric materials that can change their shapes, mechanical responses, light transmissions, controlled releases, and other functional properties under…
OPTIMIZATION OF RESULTS AND TREATMENT TIMING OF DEEP DERMAL BURNS IN CHILDREN
- K. A. Afonichev, Афоничев Константин Александрович, O. Filippova, Филиппова Ольга Васильевна, E. V. Tsvetaev, Цветаев Евгений Викторович
- 15 June 2014
The analysis of the treatment results showed that the use of early surgery in children with deep dermal burns can reduce treatment time, as well as significantly to improve the cosmetic and functional outcomes of trauma.
Selecting drug formulation for the treatment and prevention of retinal disorders
- O. Filippova
- MedicineClinical Ophthalmology
The influence of the concentration of montmorillonite containing sorbent and pH of the culture medium on the antibiotic sensitivity of Escherichia coli, as well as the effect of ground on growth of…
- V. Bukhanov, A. Vezentsev, A. Tishin
It was found that the montmorillonitebased sorbent has no antibacterial and growth-boosting action against E. coli, while the sorbent effectively accumulates on the surface of live bacteria E. Escherichia coli.
Phytoestrogens: Prospects of Use
- O. Filippova
- 13 August 2020
[2-(2'-hydroxy 2'-substituted) ethyl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines--a novel group of substances with anti-arrhythmia activity].
- O. Filippova, S. Kryzhanovskii, K. Reznikov
- Chemistry, BiologyЭкспериментальная и клиническая фармакология
Two most promising compounds (PV-168 PV-174) are characterized by a high antiarrhythmic activity, a broad spectrum of action, and low toxicity.