O. Farokhzad

Publications291
h-index102
Citations54,607
Highly Influential Citations770
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • R. Langer
  • 1,400 Publications • 177,354 Citations
  • M. Mahmoudi
  • 347 Publications • 26,692 Citations
  • Wei Tao
  • 166 Publications • 10,993 Citations
  • Jinjun Shi
  • 127 Publications • 13,121 Citations
  • Publications
  • Influence
Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles
TLDR
These factors have been shown to substantially affect the biodistribution and blood circulation half-life of circulating nanoparticles by reducing the level of nonspecific uptake, delaying opsonization, and increasing the extent of tissue specific accumulation.
Nanocarriers as an emerging platform for cancer therapy.
TLDR
The arsenal of nanocarriers and molecules available for selective tumour targeting, and the challenges in cancer treatment are detailed and emphasized.
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology.
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo.
TLDR
The potential utility of nanoparticle-aptamer bioconjugates for a therapeutic application is demonstrated and remarkable efficacy and reduced toxicity as measured by mean body weight loss (BWL) in vivo are demonstrated.
Cancer nanomedicine: progress, challenges and opportunities
TLDR
Novel engineering approaches are discussed that capitalize on the growing understanding of tumour biology and nano–bio interactions to develop more effective nanotherapeutics for cancer patients.
Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform.
We report the engineering of a novel lipid-polymer hybrid nanoparticle (NP) as a robust drug delivery platform, with high drug encapsulation yield, tunable and sustained drug release profile,…
Microfluidic platform for controlled synthesis of polymeric nanoparticles.
TLDR
This work used rapid and tunable mixing through hydrodynamic flow focusing in microfluidic channels to control nanoprecipitation of poly(lactic- co-glycolic acid)- b-poly(ethylene glycol) diblock copolymers as a model polymeric biomaterial for drug delivery.
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release.
Nanoparticle delivery of cancer drugs.
TLDR
The various nanoparticles drug delivery platforms and the important concepts involved in nanoparticle drug delivery are discussed and the clinical data on the approved nanoparticle therapeutics as well as the nanotherapeutics under clinical investigation are reviewed.
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery.
...
1
2
3
4
5
...