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Straight-chain naltrexone ester prodrugs: diffusion and concurrent esterase biotransformation in human skin.
Naltrexone (NTX) is an opioid antagonist used for treatment of narcotic dependence and alcoholism. Transdermal naltrexone delivery is desirable to help improve patient compliance. The purpose of thisExpand
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A phytochemical investigation of Homalium ceylanicum.
Vacciniin [4] (6-O-benzoyl-D-glucopyranoside) and two new benzenoid glucosides, homaloside A [1] (1''-O-benzyl-3''-O-benzoyl-alpha-L-arabinopyranosyl(1'''-->4'')- beta-D-glucopyranoside) andExpand
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Antifungal and molluscicidal saponins from Serjania salzmanniana.
An investigation of Serjania salzmanniana for biologically active substances has led to the isolation of two novel saponins, salzmannianoside A (3-O-[[beta-D-Expand
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Phenolic, iridoid and ionyl glycosides from Homalium ceylanicum
Abstract Salireposide, salirepin and two related novel phenolic glycosides named homaloside B [1-(2-methoxybenzoyloxy)methyl-5-hydroxyphenyl-β- d - glucopyranoside] and homaloside CExpand
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Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
The cyclooxygenase activity of the membrane protein prostaglandin H2 synthase isoform 1 (PGHS-1) is the target of the nonsteroidal antiinflammatory drugs (NSAIDs). The X-ray crystal structures ofExpand
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