• Publications
  • Influence
Curcumin Treatment Suppresses IKKβ Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study
Purpose: To determine whether curcumin would inhibit IκB kinase β (IKKβ) kinase activity and suppress expression of proinflammatory cytokines in head and neck squamous cell carcinoma cancer (HNSCC)Expand
  • 69
  • 6
  • PDF
Micelle-vesicle transition of egg phosphatidylcholine and octyl glucoside.
The dissolution and formation of egg phosphatidylcholine (PC) vesicles by the detergent octyl glucoside were examined systematically by using resonance energy transfer between fluorescent lipidExpand
  • 156
  • 4
Pharmacogenomics of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and the Cystic Fibrosis Drug CPX Using Genome Microarray Analysis
BackgroundCystic fibrosis (CF) is the most common lethal recessive disease affecting children in the U.S. and Europe. For this reason, a number of ongoing attempts are being made to treat the diseaseExpand
  • 72
  • 4
Transcriptome and Proteome Analyses of TNFAIP8 Knockdown Cancer Cells Reveal New Insights into Molecular Determinants of Cell Survival and Tumor Progression.
Tumor necrosis factor-α-inducible protein 8 (TNFAIP8) is the first discovered oncogenic and an anti-apoptotic member of a conserved TNFAIP8 or TIPE family of proteins. TNFAIP8 mRNA is induced byExpand
  • 28
  • 3
Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells.
Cystic fibrosis (CF) is a fatal, autosomal, recessive genetic disease that is characterized by profound lung inflammation. The inflammatory process is believed to be caused by massive overproductionExpand
  • 88
  • 2
  • PDF
The significance of TNFAIP8 in prostate cancer response to radiation and docetaxel and disease recurrence
TNFAIP8 is a NF‐κB‐inducible, oncogenic molecule. Previous “promoter array” studies have identified differential methylation and regulation of TNFAIP8 in prostate epithelial and cancer cell lines.Expand
  • 52
  • 2
Control of the Proinflammatory State in Cystic Fibrosis Lung Epithelial Cells by Genes from the TNF-αR/NFκB Pathway
BackgroundCystic fibrosis (CF) is the most common, lethal autosomal recessive disease affecting children in the United States and Europe. Extensive work is being performed to develop both gene andExpand
  • 75
  • 1
Serum proteomic signature for cystic fibrosis using an antibody microarray platform.
Antibody microarrays are a new proteomic technology, which we have developed as a platform for identifying a cystic fibrosis (CF)-specific serum proteomic signature. Serum samples from CF patientsExpand
  • 76
  • 1
Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation
A significant fraction of disease‐causing mutations affects pre‐mRNA splicing. These mutations can generate both aberrant and correct transcripts, the level of which varies among different patients.Expand
  • 70
  • 1
  • PDF
ANXA7 expression represents hormone‐relevant tumor suppression in different cancers
Tumor suppressor function of ubiquitously expressed Annexin‐A7, ANXA7 (10q21) that is involved in exocytosis and membrane fusion was based on cancer prone phenotype in Anxa7(+/−) mice as well asExpand
  • 49
  • 1