O. Efremenkova

Publications68
h-index11
Citations469
Highly Influential Citations16
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A versatile synthesis of highly bactericidal Myramistin® stabilized silver nanoparticles.
TLDR
In vitro bactericidal tests showed that Myramistin(®) capped silver NPs exhibited notable activity against six different microorganisms-gram-positive and gram-negative bacteria, yeasts and fungi. Expand
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
TLDR
It is demonstrated that the antibiotic amicoumacin A (AMI) is a potent inhibitor of protein synthesis and simultaneous interactions of AMI with 16S rRNA and mRNA and the in vivo experimental evidence suggest that it may inhibit the progression of the ribosome along mRNA. Expand
[Regulators of development in Streptomyces coelicolor A3(2)].
N-methylphenylalanyl-dehydrobutyrine diketopiperazine, an A-factor mimic that restores antibiotic biosynthesis and morphogenesis in Streptomyces globisporus 1912-B2 and Streptomyces griseus 1439
TLDR
The cell-free extracts of a landomycin E-producing strain, Streptomyces globisporus 1912-2, were shown to contain a low-molecular-weight compound that restored the landomycus E and streptomycin biosynthesis and sporulation of the defective mutants S. griseus NBRC 13350, and an explanation for the observed biological activity of MDD was proposed. Expand
5-(4-alkyl-1,2,3-triazol-1-yl)methyl derivatives of 2′-deoxyuridine as inhibitors of viral and bacterial growth
A series of 5-(4-alkyl-1,2,3-triazol-1-yl)methyl derivatives of 2′-deoxyuridine have been synthesized by the interaction of 3′,5′-diacetyl-5-azidomethyl-2′-deoxyuridine with the corresponding… Expand
Morphological characteristics of natural strains of certain species of basidiomycetes and biological analysis of antimicrobial activity under submerged cultural conditions
TLDR
It was established that, under submerged cultivation, antimicrobial substances were formed by 13 strains of 12 fungal species that were efficacious against bacterial test strains, including the methicillin-resistant strain Staphylococcus aureus and the strain Leuconostoc mesenteroides VKPM B-4177 that is resistant to the glycopeptide antibiotics. Expand
[Identification and Antagonistic Properties of the Soil Streptomycete Streptomyces sp. 100].
TLDR
The morphological, cultural, physiological, biochemical and molecular genetic characteristics of the soil streptomycete let to identify it as Streptomyces netropsis (Finlay et al., 1951) IMV Ac-5025 (UCM Ac-2186) that is an active antagonist IMVs Ac- 5025 against plant pathogens. Expand
Attenuation-Based Dual-Fluorescent-Protein Reporter for Screening Translation Inhibitors
TLDR
Dual-fluorescent-protein genes for red fluorescent protein and cerulean fluorescent protein were used as a sensor and internal control of gene expression to create a reporter construct that could be used for high-throughput screening of translation inhibitors. Expand
Sorting Out Antibiotics' Mechanisms of Action: a Double Fluorescent Protein Reporter for High-Throughput Screening of Ribosome and DNA Biosynthesis Inhibitors
TLDR
A double-reporter system for not only antimicrobial activity detection but also simultaneous sorting of potential antimicrobials into those that cause ribosome stalling and those that induce the SOS response due to DNA damage is created. Expand
Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides.
TLDR
Two sets of pyrimidine nucleoside derivatives bearing extended alkyloxymethyl or alkyltriazolidomethyl substituents at position 5 of the nucleobase were synthesized and evaluated as potential antituberculosis agents and effectively inhibited the growth of two Mycobacterium tuberculosis strains. Expand
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