A versatile synthesis of highly bactericidal Myramistin® stabilized silver nanoparticles
- G. Vertelov, Y. Krutyakov, O. Efremenkova, A. Olenin, G. Lisichkin
- ChemistryNanotechnology
- 3 September 2008
In vitro bactericidal tests showed that Myramistin(®) capped silver NPs exhibited notable activity against six different microorganisms-gram-positive and gram-negative bacteria, yeasts and fungi.
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
- Y. Polikanov, I. Osterman, P. Sergiev
- Biology, ChemistryMolecules and Cells
- 20 November 2014
[Regulators of development in Streptomyces coelicolor A3(2)].
- L. N. Anisova, I. N. Blinova, O. Efremenkova, Iu P Koz'min, V. V. Onoprienko
- BiologyИзвестия Российской академии наук Серия биологическая
- 1984
N-methylphenylalanyl-dehydrobutyrine diketopiperazine, an A-factor mimic that restores antibiotic biosynthesis and morphogenesis in Streptomyces globisporus 1912-B2 and Streptomyces griseus 1439
- B. Matselyukh, F. Mohammadipanah, H. Laatsch, J. Rohr, O. Efremenkova, V. Khilya
- Chemistry, BiologyJournal of antibiotics (Tokyo. )
- 9 July 2014
The cell-free extracts of a landomycin E-producing strain, Streptomyces globisporus 1912-2, were shown to contain a low-molecular-weight compound that restored the landomycus E and streptomycin biosynthesis and sporulation of the defective mutants S. griseus NBRC 13350, and an explanation for the observed biological activity of MDD was proposed.
[Identification and Antagonistic Properties of the Soil Streptomycete Streptomyces sp. 100].
- L. Biliavska, T. A. Efimenko, O. Efremenkova, V. Y. Koziritska, G. Iutynska
- Biology, MedicineMikrobiolohichnyi zhurnal
- 1 March 2016
The morphological, cultural, physiological, biochemical and molecular genetic characteristics of the soil streptomycete let to identify it as Streptomyces netropsis (Finlay et al., 1951) IMV Ac-5025 (UCM Ac-2186) that is an active antagonist IMVs Ac- 5025 against plant pathogens.
Synthesis of water-soluble prodrugs of 5-modified 2ʹ-deoxyuridines and their antibacterial activity
- S. Negrya, M. Jasko, L. Alexandrova
- ChemistryJournal of antibiotics (Tokyo. )
- 14 January 2020
A set of pyrimidine nucleoside derivatives bearing extended alkyltriazolylmethyl substituents at position 5 of the nucleic base showed their significant activity against Mycobacterium tuberculosis virulent laboratory strain H37Rv as well as drug-resistant MS-115 strain.
Morphological characteristics of natural strains of certain species of basidiomycetes and biological analysis of antimicrobial activity under submerged cultural conditions
- M. Dyakov, O. Kamzolkina, O. Efremenkova
- BiologyMicrobiology
- 20 April 2011
It was established that, under submerged cultivation, antimicrobial substances were formed by 13 strains of 12 fungal species that were efficacious against bacterial test strains, including the methicillin-resistant strain Staphylococcus aureus and the strain Leuconostoc mesenteroides VKPM B-4177 that is resistant to the glycopeptide antibiotics.
5-(4-alkyl-1,2,3-triazol-1-yl)methyl derivatives of 2′-deoxyuridine as inhibitors of viral and bacterial growth
- L. Alexandrova, O. Efremenkova, S. Kochetkov
- Chemistry, BiologyRussian journal of bioorganic chemistry
- 1 November 2016
The 2′-deoxyuridine derivatives exhibited an antiherpetic activity in vitro toward two laboratory strains of human herpes simplex virus type 1 and acyclovir-resistant (HSV-1/L2RACV), and a low cytotoxicity of the compounds has been shown.
Development of Antimicrobial Therapy Methods to Overcome the Antibiotic Resistance of Acinetobacter baumannii
- O. Kisil, T. A. Efimenko, N. Gabrielyan, O. Efremenkova
- Medicine, BiologyActa Naturae
- 27 October 2020
This review looks at the various attempts that have been made to tackle the problem of drug resistance relating to A. baumannii variants without the use of antibiotics.
Looking Back to Amycolatopsis: History of the Antibiotic Discovery and Future Prospects
- O. Kisil, T. A. Efimenko, O. Efremenkova
- BiologyAntibiotics
- 1 October 2021
The complete genome sequences of the Amycolatopsis demonstrate a wide variety of biosynthetic gene clusters, which highlights the potential ability of actinomycetes of this genus to produce new antibiotics.
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