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Toxic and repellent effects of Baccharis salicifolia essential oil on Tribolium castaneum.
TLDR
Toxic and repellent effects of chemical derivatives of the major sesquiterpene present in B salicifolia essential oil, as well as a series of monoterpenes, were evaluated in order to investigate structure-activity relationships. Expand
Insecticidal effects of Flourensia oolepis Blake (Asteraceae) essential oil
TLDR
Flourensia oolepis Blake (Asteraceae) essential oil had repellent and toxic effects on Tribolium castaneum Herbst adults, acting as a contact toxin. Expand
Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines.
TLDR
A series of analogs were synthesized in a straightforward manner from naturally available sesquiterpenes ilicic acid and tessaric acid, and cell cycle studies indicated a prominent arrest of the cell cycle at the G(2)/M phase. Expand
Sesquiterpenes from Tessaria absinthioides
Abstract The sesquiterpenes tessaric acid, 2-deoxytessaric acid, ilicic acid, 3-oxo-4,11(13)-eudesmadien-12-oic acid and 3β,5α-dihydroxycostic acid have been isolated from the aerial parts ofExpand
CHEMICAL COMPOSITION OF ESSENTIAL OIL OF BACCHARIS SALICIFOLIA (RUIZ & PAVON) PERS. AND ANTIBACTERIAL ACTIVITY
The essential oil of the aerial parts of Baccharis salicifolia was examined by GC and GC-MS and the major components were identified as α-pinene, camphene, β-pinene, α-phellandrene, α-cubebene,Expand
The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells.
TLDR
Overall the results point to the relevant role of the tert-butyl dimethyl silyl group in the modulation of cytotoxic activity. Expand
Gastric Anti-ulcer Activity of Several α, β-Unsaturated Carbonyl Compounds in Rat
The gastric cytoprotective activity of several molecules containing an α, β-unsaturated carbonyl system is reported. We attributed this gastroprotective activity to the presence of a non-hinderedExpand
Direct stereoselective synthesis of enantiomerically pure anti-β-amino alcohols.
TLDR
Enantiomerically pure anti-β-amino alcohols were synthesized from optically pure α-(N,N-dibenzylamino)benzyl esters by the sequential reduction to aldehyde with DIBAL-H at -78 °C and subsequent in situ addition of Grignard reagents. Expand
Derivatives of grindelic acid: from a non-active natural diterpene to synthetic antitumor derivatives.
TLDR
Using several reactions that include homologations and asymmetric epoxidations as well as Ugi and Huisgen couplings, a small focused library of new derivatives from the labdane-type diterpene grindelic acid were generated and proved to be the most active product in all cell lines tested. Expand
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