O. Bain

Publications348
h-index43
Citations6,301
Highly Influential Citations241
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Mapping the presence of Wolbachia pipientis on the phylogeny of filarial nematodes: evidence for symbiont loss during evolution.
Wolbachia pipientis is a bacterial endosymbiont associated with arthropods and filarial nematodes. In filarial nematodes, W. pipientis has been shown to play an important role in the biology of the… Expand
Integrated taxonomy: traditional approach and DNA barcoding for the identification of filarioid worms and related parasites (Nematoda)
TLDR
DNA barcoding is proposed as a reliable, consistent, and democratic tool for species discrimination in routine identification of parasitic nematodes and the coherence between DNA-based and morphological identification for almost all the species examined is very strong. Expand
The evolutionary expansion of the Spirurida.
  • A. Chabaud, O. Bain
  • Biology, Medicine
  • International journal for parasitology
  • 1 December 1994
TLDR
The available evidence suggests a complex origin of these nematodes, some families being derived from the Seuratoidea, and others from the Cosmocercoidea (Ascaridida), which seems to have occurred primarily in the Secondary or early Tertiary eras. Expand
Maturation of the filaria Litomosoides sigmodontis in BALB/c mice; comparative susceptibility of nine other inbred strains.
TLDR
Results show that the Major Histocompatibility Complex only modulates the developmental pattern of filariae within the limits imposed by background genes and male CBA/HN and C3H/HeN were more susceptible to infection than female mice. Expand
New Insights into the Evolution of Wolbachia Infections in Filarial Nematodes Inferred from a Large Range of Screened Species
TLDR
The absence of Wolbachia in 63% of onchocercids, notably in the ancestral Oswaldofilariinae estimated 140 mya old, the diverse tissues or specimens distribution, and a recent lateral transfer in supergroup F WolbachIA modify the current view on the role and evolution of the endosymbiont and their hosts. Expand
Murine filariasis: interleukin 4 and interleukin 5 lead to containment of different worm developmental stages
TLDR
IL-5 has a greater impact on parasite containment than IL-4, and IL-5 dependent effector pathways operate against different stages of filarial worms, and microfilaraemia was greatly enhanced and prolonged compared to wild-type mice. Expand
Of Mice, Cattle, and Humans: The Immunology and Treatment of River Blindness
TLDR
This review highlights the development of two animal model systems that have allowed significant advances in recent years and hold promise for the future in terms of ability to control the human disease. Expand
New and Known Species of Litomosoides (Nematoda: Filarioidea): Important Adult and Larval Characters and Taxonomic Changes
TLDR
This study confirms the close morphological resemblance between the species of Litomosoides from flying and terrestrial mammals and reinforces the hypothesis of host-switching in the evolution of this genus. Expand
Molecular phylogenetic studies on filarial parasites based on 5S ribosomal spacer sequences.
TLDR
The analyses indicated that L. sigmodontis and A. viteae may be the most primitive among the 16 species studied and the data did not show any close relationship between Loa loa and D. immitis presently classified in the same subfamily, and the constitution of the Dirofilariinae subfamily is questionable. Expand
Filarial Parasites Develop Faster and Reproduce Earlier in Response to Host Immune Effectors That Determine Filarial Life Expectancy
During larval development, filarial nematodes adjust their lifelong reproductive strategy to the presence of anti-parasitic immune cells that determine host resistance and experimental vaccine… Expand
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