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Evaluation of the quality of ditilin (suxamethonium iodide) preparations with respect to host impurities
Suxamethonium iodide is a succinic acid derivative that is widely used in medicine. In particular, the injection forms of this drug (e.g., bis-[2-(trimethylammonium)ethyl]succinate diiodide) are used
Recommendations for the Contents of the “Peptide Mapping” Part of a Product Specification File
  • O. A. Vaganova
  • The Bulletin of the Scientific Centre for Expert…
  • 2 December 2021
‘Identification. Peptide mapping’ is a necessary part of manufacturers’ product specification files for therapeutic proteins (active ingredients and final products of monoclonal antibodies,
[Preclinical investigation and standardization of metronidazole soft dosage forms].
TLDR
Comparative acute and subacute toxicity of Dentamet gel and Metrovagin suppositories manufactured by ZAO Altaivitaminy was studied and it was shown that the drugs induced no changes in the exterior, hair state, body weight and mobility of the experimental animals vs. the control.
Problems of Establishing Limits for Arsenic Content in Brown Algae and Brown Algae-Containing Medicinal Products
Algae tend to accumulate elemental toxic substances in high concentrations. Algae are widely used in the food and pharmaceutical industries, and this dictates the need to establish limits for the
Recommendations for the Contents of the “Glycan Profile” Part of a Product Specification File
  • O. A. Vaganova
  • The Bulletin of the Scientific Centre for Expert…
  • 2 December 2021
“Glycan Profile” is a necessary part of manufacturers’ product specification files for monoclonal antibody active ingredients or final products and erythropoietin active ingredients. The expert of