O T Akishpaeva

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Adsorption and penetration into chick fibroblast cells of WSN virus with completely cleaved hemagglutinin precursor (virus grown in chick embryos), partially cleaved hemagglutinin precursor (virus grown in chick fibroblasts), and virus treated with trypsin added to infected cells or virions were studied. Treatment with trypsin in both instances resulted in(More)
Maturation of virus-specific hemagglutinin and neuraminidase polypeptides was studied in chick embryo fibroblasts infected with influenza A virus, the WSN strain. Hemagglutinin maturation is accompanied by a decrease in the electrophoretic mobility of the protein. The processes occurring in maturation are localized on the part of the molecule corresponding(More)
Several classes of previously unknown virus-induced proteins were found in cells of monolayer chick embryo and MDCK cultures infected with influenza A0/WSN virus. One of them, HAb, is a hemagglutinin precursor and appears to contain less sugar residues than the mature molecule. HAb leads to HA processing occurs during transportation of the precursor from(More)
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