O. S. Sezgin

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BACKGROUND The prevalence of Helicobacter pylori (H pylori) in Turkey is high and eradication rates are low. As a result, alternative treatment strategies are required. OBJECTIVES To evaluate the status of H pylori eradication in Turkey by comparing the results of this study to other studies reported in the literature. METHODS Two hundred and eighty-two(More)
Recently, circulating miRNAs have been reported as promising biomarkers for various pathologic conditions including cancer. Certain microRNAs (miRNAs) have been shown early diagnostic potential for many types of cancer. The objective of this study was to investigate the potential of certain serum/plasma miRNAs as novel non-invasive biomarkers for early(More)
The autosomal-recessive form of popliteal pterygium syndrome, also known as Bartsocas-Papas syndrome, is a rare, but frequently lethal disorder characterized by marked popliteal pterygium associated with multiple congenital malformations. Using Affymetrix 250K SNP array genotyping and homozygosity mapping, we mapped this malformation syndrome to chromosomal(More)
BACKGROUND/AIMS Helicobacter pylori is the most common infectious disease all over the world. Ten to twenty percent of the patients remain infected despite treatment with proton pump inhibitors (PPIs), amoxicillin and clarithromycin. We compared PPI, bismuth, tetracycline and metronidazole with ranitidine bismuth citrate, tetracycline and metronidazole in(More)
Heterotopic pancreas is defined as the presence of pancreatic tissue that lacks anatomic and vascular continuity with the main body of the pancreas. Frequent symptoms and signs are epigastric pain, abdominal fullness and tarry stools. The most frequent locations of heterotopic pancreas tissue are the stomach and jejunum; however, there are a few reported(More)
TO THE EDITOR: Pemphigus vulgaris (PV) is a rare disorder of stratified squamous epithelium in which autoantibodies are directed against a keratinocyte cell surface antigen, various adhesion molecules of the epidermis or dermoepidermal basement membrane zone, desmoglein 3, and other self-antigens (1–3). The skin and oral mucosa are most commonly involved,(More)
BACKGROUND/AIMS Helicobacter pylori infection has a high prevalence and is considered an important health problem in Turkey. Unfortunately, an effective treatment has not yet been found for the eradication of Helicobacter pylori infection, at least in our country. Standard therapies recommended for the eradication of Helicobacter pylori have failed in the(More)
Penetration of a recurrent ulcer into the anterior abdominal wall after surgical treatment of peptic ulcer disease is a rare surgical emergency. Early diagnosis is essential, but there are no specific radiographic or endoscopic features. We report 2 cases of recurrent ulcer penetration into the anterior abdominal wall diagnosed preoperatively with(More)
BACKGROUND Symptomatic biliary obstruction caused by cavernous transformation of the portal vein is an extremely rare disorder for which there is no consensus as to optimal treatment. The results of endoscopic treatments in a small group of patients is reviewed. METHODS A total of 10 patients (5 men, 5 women; mean age 36.1 years, range 17-48 years) with(More)
Recently, serum miRNAs have been evolved as possible biomarkers for different diseases including hepatocellular carcinoma and other types of cancers. Investigating certain serum miRNAs as novel non-invasive markers for early detection of HCV-positive cirrhosis and hepatocellular carcinoma (HCC). The expression profiles of 58 miRNA were analyzed in patient’s(More)