O. N. Tsys'

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The mechanisms of the hypotensive effect of portocaval transposition were investigated in dogs with vasorenal hypertension. Directing blood flowing from the kidneys and adrenals into the liver in dogs with vasorenal hypertension was found to increase aldosterone metabolism and, at the same time, to increase aldosterone secretion by the adrenals, as a result(More)
The study concerns the effect of angiotensin II when infused into the systemic and portal blood flow upon the general and renal haemodynamics in normal dogs and in hypertensive animals, as well as the effect of the operation of porto-caval transposition upon the course of renovascular hypertension. When peptide is infused, at a rate that causes a moderate(More)
The effect of portocaval transposition (PCT) on the general hemodynamics was studied in intact dogs and in dogs with experimental vasorenal hypertension. In the experimental dogs the arterial pressure fell after PCT chiefly on account of a decrease in the peripheral vascular resistance to the blood flow. In healthy dogs PCT caused no substantial changes in(More)
The authors studied changes in the general hemodynamics in healthy nonanesthetized dogs in infusion of 27/ng/kg/min of angiotensin II into the superior vena cava and the portal vein. Portal infusion of the peptide produced a less pronounced pressor effect. Elevation of arterial pressure in systemic infusion of angiotension occurred on account of increase in(More)
Changes in the general hemodynamics were studied in healthy unanesthetized dogs after injection of angiotensin II for 60 min into the superior vena cava and portal vein at the rate of 27 ng/kg/min. Portal administration of the peptide was found to induce a weaker pressor effect. After systemic injection of angiotensin II the arterial pressure rose as the(More)
Experiments were conducted on unanesthetized dogs; the influence of portocaval transposition on the systemic hemodynamics of the intact dogs and dogs with experimental vasorenal hypertension was studied. Arterial pressure was decreased in dogs with vasorenal hypertension after portocaval transposition mainly by means of reduction of the total peripheral(More)
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