O L Smirnova

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Olicard-Retard, isosorbide-5-mononitrate drug, has been tried in a single daily dose 40 mg in 60 outpatients with angina pectoris. The drug reduced the frequency of anginal attacks and nitroglycerine intake in most of the patients. The antianginal properties were combined with anti-ischemic effects as shown by echocardiography. Side effects (head ache) were(More)
Sedacorone (amiodarone) was given to 70 outpatients with coronary heart disease for 1.5-2 years to prevent paroxysms of cardiac arrhythmia after recovery of sinus rhythm. Sedacorone was administered initially in the dose 600 mg/day for 10-12 days, then the dose lowering was adjusted to the tolerance, heart rate and ECG readings. The minimal dose of 200(More)
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