O L Erukainure

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The recent resurgence of interest in the study of mitochondria has been fuelled in large part by the recognition that genetic and/or metabolic alterations in this organelle are causative or contributing factors in a variety of human diseases including cancer. This study hypothesizes that co-administration of artesunate and ferrous sulfate could induce(More)
Antilipemic/hypocholestermic activities of the methanolic extracts of Globimetula braunii were studied in the tissues of normo and hypercholesteremic rats. Hypercholesteremia was induced in the rats by feeding with dietary cholesterol at a dose of 40 mg/kg body weight. A significant increase (p<0.05) was observed in the body and the visceral organs relative(More)
OBJECTIVE To investigate the ability of the methanolic extract of pineapple peel to modulate alcohol-induced lipid peroxidation, changes in catalase activities and hepatic biochemical marker levels in blood plasma. METHODS Oxidative stress was induced by oral administration of ethanol (20% w/v) at a dosage of 5 mL/kg bw in rats. After 28 days of(More)
The chemical properties of the African palm weevil, Rhychophorus phoenicis (F.) (Coleoptera: Curculionidae), larvae were evaluated using standard methodology. The chloroform-methanol extract yielded 37.12% on a dry basis. The oil was liquid at room temperature with a flash point of 36.0 °C. Analysis of the physical constants indicated values of 192.25 Wijs(More)
Recent advances in functional foods-based research have increasingly become an area of major interest because it affects human health and activities. Functional foods are classes of foods with health promoting and disease preventing properties in addition to multiple nutritional values and of such type is honey. Acacia honey is a type of honey produced by(More)
Lung cancer is one of the leading causes of death worldwide. We investigated the molecular mechanism of antiproliferation potential of Acacia honey on NCI-H460 cells by cell cycle, viability, cytokines, calcium ion and gene expression analysis. Acacia honey inhibited cells proliferation, arrested G0/G1 phase, stimulated cytokines, calcium ion release as(More)
The cardiovascular protective and hypolipidemia effects of soybean oil were investigated in normocholesteremic rats. Diets were prepared and designed to contain 50 % of energy as carbohydrate, 35 % as fat, and 15 % as protein. Groups of six rats were each fed one of these diets, while a group was fed pelletized mouse chow which served as the control. A(More)
High-quality cassava starch (HQCS) produced from high-yielding low-cyanide improved cassava variety, TMS 30572, was mixed with durum wheat semolina (DWS) on a replacement basis to produce flour samples containing 0, 20, 30, 50, 70, and 100% cassava starch. They were analyzed for chemical composition (proximate, amylose, free sugars, starch, wet gluten, and(More)
AIM This study aims at reporting the isolation, structure elucidation, and antioxidant potentials of ajugoside from C. volubile leaves in sodium nitroprusside (SNP)-induced oxidative stressed rat brain and hepatic tissues. MATERIALS AND METHOD An iridoid monoterpene, ajugoside was isolated from the n-butanol fraction of C. volubile and evaluated for its(More)
The antiproliferative effect of the fatty acid components of Clerodendrum volubile leaves as well as its antioxidant effect on MCF-7 and MDA-MB-231 human breast cancer cell lines were investigated. Fatty acids extracted from C. volubile leaf oil were subjected to gas chromatography mass spectrometry (GCMS) analysis. The cells were cultured and treated with(More)