O. L. Cremer

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Methods Data were derived from a prospective cohort study in two tertiary ICUs in the Netherlands in 2011 and 2012. Patients were included if they had survived one year following a sepsis episode in the ICU. Health care consumption and reimbursed costs were derived from a database of a Dutch health insurance company. The medical ethics committee of the UMC(More)
Introduction: A hallmark of sepsis is early onset microvascular dysfunction. However, the mechanism responsible for maldistribution of capillary blood flow is not understood. Evidence suggests red blood cells (RBC) can sense local oxygen (O2) conditions and signal the vasculature, via adenosine triphosphate (ATP), to increase capillary flow. We hypothesized(More)
Unfortunately, the original version of this supplement [1] contained errors in two of the abstracts; P037 and P127. Please see details below. In P037, the image presented as Figure eight is incorrect. The correct figure is shown below (Fig. 1). In P127, the author list presented is incorrect. The correct author list is as below. R Iqbal; Y Alhamdi; N(More)
RATIONALE We hypothesised that patients with acute respiratory distress syndrome (ARDS) can be clustered based on concentrations of plasma biomarkers and that the thereby identified biological phenotypes are associated with mortality. METHODS Consecutive patients with ARDS were included in this prospective observational cohort study. Cluster analysis of(More)
Methods Retrospective analysis of an ICU cohort with ongoing prospective assessment of VAP in 2 academic medical centers (January 2011 – June 2012). The VAE algorithm was electronically implemented as specified by NHSN and includes assessment of (infection-related) ventilatorassociated conditions (VAC, IVAC) and possible or probable VAP. Incidence and(More)
The incidence of respiratory syncytial virus (RSV) and influenza virus infection was determined during three RSV seasons in 158 adult patients consecutively admitted to the intensive care unit with community-acquired respiratory failure. Nasopharyngeal swabs were tested for the presence of RSV and influenza virus by real-time polymerase chain reaction. Six(More)