O. Kashimura

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  • O. Kashimura
  • Nihon eiseigaku zasshi. Japanese journal of…
  • 1993
This study examined alterations in the degree of exposure to cold and the pulmonary arterial pressure in awake, catheter-implanted rats. Seven male Wistar rats weighing 280 to 300 g were used. Two special hand-made catheters were inserted into the pulmonary artery and the level of the aortic arch, respectively. Each animal was exposed once to each of four(More)
We examined the effects of exercise training on pulmonary arterial blood pressure (Ppa) and on adenosine 3′,5′-cyclic monophosphate (cAMP) and guanosine 3′,5′-cyclic monophosphate (GMP) concentrations in lung tissue at rest and during exercise under hypoxic conditions in catheter-implanted rats. Male Wistar rats were divided into an exercise-trained group(More)
  • O. Kashimura
  • Environmental health and preventive medicine
  • 1998
We investigated the responses of thoracic aortae to adrenergic contraction and endothelium-dependent relaxation following chronic exposure to cold in rats. Two groups (CA, cold-acclimated for 12 weeks at 5 °C; WA, warm-acclimated for 12 weeks at 24 °C) of 10 male Sprague-Dawley rats were used. After anesthesia, the thoracic aortae (4 mm long) were isolated(More)
  • O. Kashimura
  • Nihon eiseigaku zasshi. Japanese journal of…
  • 1995
The objectives of the present study are to directly measure the pulmonary and systemic arterial pressures in unanesthetized, and unrestrained rats during exposure to cold and to assess pulmonary vascular responsiveness to administration of the alpha-and beta-adrenergic receptor antagonists phenoxybenzamine (1mg/kg, i.v.) and propranolol (20 micrograms/kg,(More)
  • O. Kashimura
  • Nihon eiseigaku zasshi. Japanese journal of…
  • 1992
The present study was carried out to examine the effects of enhanced cold tolerance induced by exercise training on carbohydrate metabolism during cold exposure. Five-week-old male Wistar rats were divided into three groups. The warm-acclimated control group (WA) was exposed to the environment at 25 degrees C, and the cold-acclimated group (CA) was(More)
  • O. Kashimura
  • Environmental health and preventive medicine
  • 1999
The present study was designed to determine whether norepinephrine (NE) mediate endothelium-dependent relaxations in arteries of the pulmonary vasculature of cold-acclimated rats. Twenty male Sprague-Dawley rats comprising two groups (Cold-acclimated for 12 weeks at 6°C, CA; Warm-acclimated for 12 weeks at 24 °C, WA) were used. After anesthesia, the(More)
The present study was undertaken to compare the systemic blood pressure responses during graded acute exercise of stroke-prone spontaneously hypertensive rats (SHRSP) and normotensive Wistar-Kyoto rats (WKY). Systemic blood pressure was measured by left carotid artery catheter during exercise. Systolic blood pressure incre-ments with running exercises at(More)
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