O I Mikovskaia

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
A possibility of the long-term modification of inborn behavioral features of different mice genotypes (C57B1/6 and BALB/c) by active immunization with dopamine-bovine serum albumin conjugate was investigated. Significant interstrain differences were found in the effects of dopamine antibodies on the open-field behavior and the content of neurotransmitters(More)
The effect of active immunization with conjugated serotonin-protein on the "open-field" behaviour and passive avoidance conditioning was studied in genetically different mice strains (C57BL/6 and BALB/c). The obtained immunophysiological effects of serotonin antibodies depended on genetically determined characteristics of animal behaviour. Serotonin(More)
Dopamine antibodies (AB) were singularly injected to C57B1/6 mice intraperitoneally. The locomotor activity in the open field was suppressed for 5 days in the majority of the animals. Hyperalgesia revealed 1.5 h and 1 day after the AB injection changed for analgesia on the 5th day. A sharp reduction of the brain level of dopamine and its metabolite was(More)
Mice of C57BL/6 strain were singly injected intraperitoneally with antibodies (AB) to serotonin (5-HT). The "open-field" testing in different periods after the AB injection revealed a depression of behavior within 1.5 h which changed for activation within 1 day and, again, depression within 5 days after the injection. The analysis of neurotransmitter(More)
The antibodies to serotonin modulate behavioural reactions of animals depending on the mode of administration (intracerebroventricular or intraperitoneal) and the testing time. Intraventricular injection induces inhibition of behavioural activity within 1--2 hours. Systemic injection produces a biphasic effect on the serotoninergic system, i. e., the(More)
  • 1