O. F. Kandarakov

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The growth of malignant tumors occurs in 3D environments and depends on the presence of a stromal component, which performs critical functions of tumor-cell protection and growth support. Therefore, the development and analysis of tumor models in 3D cell cultures in vitro, including coculture systems, hold significant interest. In this study, the results of(More)
A series of experiments on co-culturing of Mel IL melanoma cells and mesenhymal stem cells showed that these cells do not influence proliferation of each other, but we observed weaker adhesion of stromal stem cells to plastic in cocultures where with melanoma cells were grown on mesenhymal stem cells feeder. Cell proliferation was also considerably(More)
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