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BACKGROUND The aim of this study was to evaluate the significance of elevated postoperative Troponin T (TnT) levels in an elderly population undergoing non-cardiac surgery. METHODS Five hundred and forty-six consecutive patients aged 70 years or older undergoing non-cardiac surgery of >30-min duration were enrolled in this prospective, observational(More)
The concentration of propofol in and surrounding the human brain during propofol anaesthesia is unknown. We measured simultaneously the concentration of propofol in cerebrospinal fluid (CSF) from an indwelling intraventricular catheter and the concentration in arterial blood in five neurosurgical patients before, during induction (at 2.5 and 5 min) and(More)
Classically haemodilution is regarded as causing coagulopathy. However, haemodilution with saline seems to cause a hypercoagulable state both in vivo and in vitro. The aim of the present study was to measure the effect of mild to severe haemodilution using thrombelastography. Blood samples were taken in 12 healthy volunteers and divided into seven aliquots.(More)
OBJECTIVE To find out if the need for transfusion was increased by volume substitution with dextran 70 in patients receiving prophylaxis against thrombosis with low molecular weight heparin. DESIGN Open randomised controlled trial. SETTING University hospital, Sweden. SUBJECTS 40 patients undergoing revision hip arthroplasty. INTERVENTIONS(More)
BACKGROUND Experimental data have suggested that hypothermia (32-34 degrees C) may improve outcome after cerebral ischaemia, but its efficacy has not yet been established conclusively in humans. In this study we examined the feasibility and safety of deliberate moderate perioperative hypothermia during operations for subarachnoid aneurysms. METHODS A(More)
The function in various types of climate of three ventilators which are commercially available in Sweden: Motivus, Pneupac 2 and Logic 07, was tested as well as their sensitivity to vibration. The ventilators functioned in subzero temperatures only if the driving gas had a low humidity content. They also required an increased driving gas pressure. Only(More)
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