O. A. Valeeva

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The study was conducted during the experiment with a 105-day isolation in an experimental complex. Urine samples were collected from six healthy volunteers. The physical activity, diurnal rhythm, temperature parameters, and levels of oxygen and carbon dioxide were controlled during the experiment. According to the program, food intake (electrolysis, water,(More)
We analyzed protein profile of urine samples obtained from 7 Russian cosmonauts (age 35-51 years), participants of space flights on the International Space Station lasting for 169-199 days. Gradient chromatography with linear increase of eluent proportion was carried out in a system consisting of an Agilent 1100 chromatograph (Agilent Technologies Inc.) and(More)
In this study we examined alterations in proteome of blood plasma of healthy persons induced by dry immersion. We studied blood plasma from 14 19- to 26-year-old healthy men sampled 7 and 2 days prior to the start, days 2, 3, and 5 of, and 1, 3, 7, and 15 days after the end of the experiment. Prior to direct MALDI-TOF spectrometric profiling, serum samples(More)
Renal function and body composition, including fluids, were studied during space flight conditions imitation with five-day dry immersion in 14 apparently healthy men. Noninvasive research of water spaces of the body was performed using methods of bioimpedance analysis (BIA). It was shown that renal excretion of fluids increased and negative aqueous balance(More)
Changes in the proteome of urine and blood serum obtained from 14 healthy humans (aged 21–29 years), medically approved for the experiment with dry immersion, have been studied. Urine and serum samples were fractionated and concentrated using MB–WCX and MB–HIC magnetic particles, respectively. Direct mass spectrometry profiling by MSLDI–TOF was carried out(More)
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