Nwora Lance Okeke

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INTRODUCTION There is increasing evidence that autoantibodies and immune complexes (ICs) contribute to synovitis in rheumatoid arthritis (RA), yet the autoantigens incorporated in ICs in RA remain incompletely characterised. METHODS We used the C1q protein to capture ICs from plasma derived from human RA and control patients. Antibodies specific for(More)
Given the widespread availability of effective antiretroviral therapy, engagement of HIV-infected persons in care is a global priority. We reviewed 51 studies, published in the past decade, assessing strategies for improving linkage to and retention in HIV care. The review included studies from highly resourced settings (HRS) and resource-poor settings(More)
BACKGROUND Persons infected with human immunodeficiency virus (HIV) are at higher risk for major cardiovascular disease (CVD) events than uninfected persons. Understanding the epidemiology of major traditional CVD risk determinants, particularly hypertension, in this population is needed. METHODS The study population included HIV-infected patients(More)
BACKGROUND Although human immunodeficiency virus (HIV)-infected persons are at increased risk for major cardiovascular events, short-term prognosis after these events is unclear. METHODS To determine the association between HIV infection and acute myocardial infarction (AMI) and stroke outcomes, we analyzed hospital discharge data from the Nationwide(More)
BACKGROUND Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections are associated with increased risk of cardiovascular disease (CVD). The potential impact of recently updated cholesterol guidelines on treatment of HIV- and HCV-infected veterans is unknown. METHODS We performed a retrospective cohort study to assess statin use and(More)
A 56-year-old man with longstanding human immunodeficiency virus (HIV) infection presented for evaluation of new-onset fatigue and malaise. He was adherent to his antiretroviral therapy (ART) regimen (tenofovir/emtricitabine, raltegravir), with a recent CD4 lymphocyte count of 382 cells/mm (18%) and HIV RNA below the level of assay detection. Initial(More)
sippi set separate age restrictions for antipsychotic entities basedon theFDA-approvedminimumpediatric age anddiagnosis criteria for these drugs. Of the 31 states, 15 have incorporated a peer review process,wherein the adjudicationprocess usually involves apsychiatrist or other physician specialty (Table 2). The programs without apeer reviewprocess use(More)
Despite an increased risk of coronary artery disease (CAD) in persons infected with human immunodeficiency virus (HIV), few data are available on primary prevention of CAD in this population. In this retrospective cohort study, HIV-infected patients treated in an academic medical center HIV Specialty Clinic between 1996 and 2010 were matched by age, gender,(More)
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