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Overexpession of EGFR has been reported in a variety of human cancers and serves as a target for diagnosis and therapy. In the case of breast cancer, about 48% EGFR and have poor clinical prognosis. Besides the prognostic factors like tumor size, nodal status, histological grade etc., which are significant in the management of breast cancer, EGFR level(More)
The C-erbB-2 proto-oncogene encodes a 185KD glycoprotein with tyrosine kinase activity. Overexpression of this gene either due to gene amplification and/or increased transcription has been observed in a variety of cancers and has been associated with more aggressive disease and a poor clinical prognosis in 20-30% of patients with breast cancer. Besides(More)
Lymphangiomas are congenital malformations of lymphatic vessels filled with a clear protein-rich fluid containing few lymph cells. It can also occur in association with hemangioma. Large lymphangioma extending into the tissue spaces of neck is referred to as cystic hygroma. Herewith, we present a case of cystic hygroma associated with lymphangioma of tongue(More)
Talon cusp occurs as a result of disturbances during the morpho-differentiation stage of tooth development. It is more common on the palatal surface of the permanent maxillary incisors. It can be unilateral/bilateral, but can also occur on the same tooth. Only 2 published reports exist documenting talons on both labial and lingual surfaces of the same tooth(More)
Anxiety is a special variety of fear, experienced in anticipation of threatening stimuli. While some research workers have said that the response of a child improves with the number of visits, many have felt otherwise. The present study is yet another effort to find the patterns of anxiety in children during sequential dental visits. The main aim was to(More)
PURPOSE To assess the prevalence of caries and the treatment needs of Down syndrome children in the Indian city of Chennai. MATERIALS AND METHODS Among the 130 Down syndrome children examined, only the children aged < or =15 years were included in the study ( n = 102). There were 57 male and 45 female children in the total study sample. A specially(More)
BACKGROUND Anxiety and fear remain the primary emotion of a child entering a dental office. Successful pediatric dentistry depends not only on the dentist's technical skills, but also on his ability to acquire and maintain a child's cooperation. METHODS A retrospective study was done using the case records of 247 children, to evaluate their behavior(More)
OBJECTIVE To provide information on the state of occlusion and the spaces available after complete eruption of the primary dentition and to compare the characteristic features of the primary dentition in Chennai and Hyderabad, two of the metropolitan cities in South India. MATERIALS AND METHODS Children in the age range between 3 and 5 years were selected(More)
Mucormycosis is one of the most rapidly progressing and lethal form of fungal infections in humans which usually begins in the nose and paranasal sinuses. The fungus assaults the arteries, leading to thrombosis that subsequently causes necrosis of hard and soft tissues. The purpose of this article is to describe a rare case of maxillary necrosis due to(More)