Floating dosage forms of acetylsalicylic acid, used for its antithrombotic effect, were developed to prolong gastric residence time and increase bioavailability. In the two-layer tablet formulation, hydroxypropyl methylcellulose (HPMC) of high viscosity and an effervescent mixture of citric acid and sodium bicarbonate formed the floating layer. The release… (More)
BACKGROUND Prolactinoma is a pituitary adenoma originating from prolactin-secreting epithelial cells of the adenohypophysis. Unfortunately, there appears to be a relatively high recurrence rate despite all pharmacological, radiological, and surgical therapeutic interventions. The aim of the present study was to evaluate the extent of involvement of the… (More)
Quantum fluctuations for a massless scalar field in the background metric of spherical impulsive gravitational waves through Minkowski and de Sitter spaces are investigated. It is shown that there exist finite fluctuations for de Sitter space.
We review our previous work on the calculation of the vacuum expectation value of the stress-energy tensor for a scalar particle in the background metric of different types of spherical impulsive, spherical shock and plane impulsive gravitational waves. We get non-zero vacuum fluctuations only if we use the spherical impulsive wave as the background. We… (More)
Unruh's detector calculation is used to study the eeect of the defect angle in a space-time with a cosmic string for both the excitation and deexcitation cases. It is found that a rotating detector results in a non-zero eeect for both nite (small) and innnite (large) time.
We extend the work done for cosmic strings on the perturbative calculation of vacuum polarization of a massless field in the space-time of multiple cosmic strings and show that for a more general class of locally flat metrics the one loop calculation do not introduce any new divergences to the VEV of the energy of a scalar particle or a spinor particle. We… (More)