Nurlan Brimkulov

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OBJECTIVE To assess the annual lung function decline associated with the reduction of secondhand smoke exposure in a high-altitude industrial workforce. METHODS We performed pulmonary function tests annually among 109 high-altitude gold-mine workers over 5 years of follow-up. The first 3 years included greater likelihood of exposure to secondhand smoke(More)
BACKGROUND Studies of occupational acute mountain sickness (AMS) have not focused on the more severe end of the spectrum to date. AIMS To examine risk factors associated with the development of occupational AMS severe enough to receive treatment in a compression chamber. METHODS A nested case referent study in a cohort of high-altitude (4000 m) mine(More)
The aim of this study was to assess how exhaled nitric oxide (NO) levels in healthy subjects changed upon exposure to intermittent hypoxia at high altitude. Eighty-one healthy subjects with a mean age of 31.8±6.7 years, well acclimatized at altitudes of 3800-4000m above sea level, and employed by a gold-mining company were recruited for the study. Baseline,(More)
SETTING Ambulatory health centres in Bishkek, Kyrgyzstan. OBJECTIVE To assess the results of training family doctors in Practical Approach to Lung Health (PAL) techniques. DESIGN Comparison of the results of two surveys, before (baseline) and after (impact) training on PAL guidelines. Both surveys were carried out according to the same protocol. (More)
OBJECTIVE We aimed to ascertain risk factors for acute mountain sickness (AMS) in miners exposed to chronic intermittent high altitude conditions. METHODS All new hires (2009-2012) for mine employment (4000 m above sea level) were followed up for 12 months after first ascent. Demographics, physiologic data, and cigarette smoking were assessed at(More)
The Practical Approach to Lung Health (PAL) strategy was adopted by the Ministry of Health of Kyrgyzstan to improve the quality of case management of priority respiratory illnesses, including tuberculosis (TB). The process of development and implementation of the strategy is described in the present study. The World Health Organization stepwise framework(More)
132 bronchial asthma patients living in Frunze (760 m above the sea level) and those on adaptation days 3-5 and 25-30 to the climate of North Tien Shan (3200 m above the sea level) underwent clinical and functional examination involving assessment of ACTH, cortisol and aldosterone levels. The patients showed clinical response and improvement of bronchial(More)
The superficial activity and cytological composition of bronchoalveolar washes off (BAW) were investigated in 55 patients with bronchial asthma. As compared to the control group the patients with bronchial asthma in remission demonstrated a moderate decrease in the superficial BAW activity which grew in the phase of exacerbation, a degree of variations of(More)
24 patients exposed to low-dose radiation after the Chernobyl accident were examined before and after 24-day treatment of chronic bronchitis in the high-altitude rehabilitation center (3200 m above the sea level) in Tien Shan. Sanogenic alpine climate improved the patients' general condition, physical performance and lung ventilation, corrected compromised(More)