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Sorafenib is a new drug, multikinase inhibitor, which has been recently approved for the treatment of metastatic renal cell carcinoma and hepatocellular carcinoma. Up to 90 percent of patients receiving this drug have been reported to develop dermatological symptoms. Recently, it has been suggested that the appearance of skin toxicity during therapy may(More)
Extramammary Paget's disease is an uncommon intraepithelial adenocarcinoma which occurs in areas rich in apocrine glands. Although surgery is the treatment of choice, numerous noninvasive treatments have been tried. There are studies that have demonstrated the efficacy of imiquimod to treat Extramammary Paget's disease, but we found no mention in the(More)
Kabuki syndrome or Kabuki makeup syndrome was first described in 1981 in Japan by two different groups of authors. These investigators described a group of patients sharing typical facial features, skeletal anomalies, mental retardation, short stature, and dermatoglyphic anomalies. The term Kabuki makeup syndrome was coined because the peculiar facial(More)
ଝ Respuesta a terapia fotodinámica en paciente con dermatosis pustulosa del cuero cabelludo y queratosis actínicas hipertróficas To the Editor: Erosive pustular dermatosis of the scalp is a rare inflamma-tory skin disease that mainly affects older patients and is characterized by the presence of sterile pustules and scabs. Recently, several authors have(More)
BACKGROUND Formaldehyde and formaldehyde-releasers are common causes of allergic contact dermatitis. OBJECTIVES To determine the frequency of sensitization to formaldehyde and seven formaldehyde-releasers. To establish and characterize groups of patients according to the results of patch testing. MATERIALS AND METHODS We performed a 5-year retrospective(More)
BACKGROUND Isolated cases of allergic contact dermatitis, gingivitis and stomatitis caused by beryllium have been previously reported. We have been able to study a series of 12 patients with patch test reactions to beryllium chloride. OBJECTIVES The study was aimed at defining the clinical and patch testing characteristics in this group of patients, and(More)
Formaldehyde is a colorless gas with a pungent odor that is widely used as a preservative in toiletries and cosmetics and in products for household and industrial use. Both formaldehyde itself and substances that can release it are a common cause of allergic contact dermatitis. This condition often becomes chronic, given that these allergens are found(More)
BACKGROUND Hand eczema is not uncommon in children but it is rarely studied using skin-prick tests. Few reports have addressed their usefulness in children and none has specifically analyzed their use in children with hand eczema. MATERIAL AND METHODS We performed a retrospective study of all children up to 16years of age with hand eczema who were(More)
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