Nunzia Tacelli

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RATIONALE AND OBJECTIVES To investigate the accuracy of dual-energy computed tomography in the depiction of perfusion defects in patients with acute pulmonary embolism (PE). MATERIALS AND METHODS One hundred seventeen consecutive patients with clinical suspicion of acute PE underwent dual-energy multidetector computed tomographic (CT) angiography of the(More)
PURPOSE To determine the energy levels that provide optimal imaging of thoracic circulation at dual-energy computed tomographic (CT) angiography with reduced iodine load in comparison with a standard technique. MATERIALS AND METHODS The institutional review board approved the study with waiver of patient consent. Eighty patients underwent a dual-source,(More)
Automated lobar quantification of emphysema has not yet been evaluated. Unenhanced 64-slice MDCT was performed in 47 patients evaluated before bronchoscopic lung-volume reduction. CT images reconstructed with a standard (B20) and high-frequency (B50) kernel were analyzed using a dedicated prototype software (MevisPULMO) allowing lobar quantification of(More)
Among the various imaging modalities available, CT has remained over time the core imaging technique for the evaluation of respiratory disorders. The recent advent of dual-source CT offers innovative approaches to investigate thoracic diseases, based on the use of one or two tubes as well as single or dual energy to scan the entire thorax. Two major options(More)
To evaluate image quality of dual-source computed tomography (CT) angiograms acquired with high temporal resolution and high pitch modes. Two groups of 70 consecutive patients underwent chest CT angiography with dual-source, single-energy CT, with an 83-ms temporal resolution and a pitch of 2 (group 1) or a pitch of 3 (group 2). Subjective and objective(More)
To determine whether CT can depict early perfusion changes in lung cancer treated by anti-angiogenic drugs, allowing prediction of response. Patients with non-small cell lung cancer, treated by conventional chemotherapy with (Group 1; n = 17) or without (Group 2; n = 23) anti-vascular endothelial growth factor (anti-VEGF) drug (bevacizumab) underwent CT(More)
PURPOSE To evaluate whether dual-energy CT angiography (DE-CTA) could identify links between morphologic and functional abnormalities in chronic pulmonary thromboembolism (CPTE). MATERIALS AND METHODS Seventeen consecutive patients with CPTE without underlying cardio-respiratory disease were investigated with DE-CTA. Two series of images were generated:(More)
Recent technological advances in multidetector computed tomography (CT) have led to the introduction of dual-source CT, which allows acquisition of CT data at the same energy or at 2 distinct tube voltage settings during a single acquisition. The advantage of the former is improvement of temporal resolution, whereas the latter offers new options for CT(More)
PURPOSE To compare peripheral pulmonary artery image quality at 80 kVp and 140 kVp in the same patients. MATERIALS AND METHODS Image quality of third-, fourth- and fifth-order arteries was assessed at 80 kV and 140 kV on 1-mm-thick transverse scans, generated from dual-source computed tomography (CT) acquisitions. RESULTS The mean level of enhancement(More)
To evaluate the assessibility of coronary arteries in respiratory patients with high heart rates. This study was based on the comparative analysis of two paired populations of 54 patients with a heart rate >70 bpm evaluated with dual-source (group 1) and single-source (group 2) CT. The mean heart rate was 89.1 bpm in group 1 and 86.7 bpm in group 2 (P =(More)