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The heart is not only our most vital, but also our most complex organ: Precisely controlled by the interplay of electrical and mechanical fields, it consists of four chambers and four valves, which act in concert to regulate its filling, ejection, and overall pump function. While numerous computational models exist to study either the electrical or the(More)
Ischemic mitral regurgitation is associated with substantial risk of death. We sought to: (1) detail significant recent improvements to the Dassault Systèmes human cardiac function simulator (HCFS); (2) use the HCFS to simulate normal cardiac function as well as pathologic function in the setting of posterior left ventricular (LV) papillary muscle(More)
The mechanical properties of Nitinol stents are normally evaluated experimentally due to complexities resulting from large deformations and material nonlinearity. Despite the difficulties associated with Finite Element Analysis (FEA), the success of the computational analysis in combination with experimental study leads to better understanding of stent(More)
Flap neovascularization is an important plastic surgery phenomenon, which allows the pedicle to achieve an alternative blood supply basis for pedicled flap autonomization. Numerous historical flaps have been described which provided the clinical evidence of its occurrence Neovascularization is assumed to happen between flap and recipient bed and numerous(More)
PURPOSE Heart failure is a worldwide epidemic that is unlikely to change as the population ages and life expectancy increases. We sought to detail significant recent improvements to the Dassault Systèmes Living Heart Model (LHM) and use the LHM to compute left ventricular (LV) and right ventricular (RV) myofiber stress distributions under the following 4(More)
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