Nuno Couto

Renata Ramalho2
Rui Bergantim1
2Renata Ramalho
1Rui Bergantim
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BACKGROUND Tachykinins substance P, neurokinin A and neurokinin B seem to account for asthma pathophysiology by mediating neurogenic inflammation and several aspects of lung mechanics. These neuropeptides act mainly by their receptors NK1, NK2 and NK3, respectively which may be targets for new asthma therapy. METHODS This review systematically examines(More)
Autologous stem cell transplantation (ASCT) is the gold standard therapy for suitable multiple myeloma (MM) patients after induction with high dose therapy. To date, the evidence of a reliable marker of prognosis in these cases remains scarce. Our aim was to evaluate appearance of unrelated atypical serum immunofixation patterns (ASIPs) as a marker of(More)
The main goal of this paper is to analyze the exergy losses during the shock and rarefaction wave of hydrogen-air mixture. First, detonation parameters pressure, temperature, density, and species mass fraction are calculated for three cases where the hydrogen mass fraction in air is 1.5%, 2.5%, and 5%. Then, exergy efficiency is used as objective criteria(More)
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