Nukala Satheesh Kumar

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Polymerase chain reaction (PCR) assay was developed for the detection of Egg drop syndrome 1976 (EDS-76) virus in tissues, namely in the uterus, spleen and buffy coat. It was also used to study the persistence of the virus in tissues of experimentally infected layer birds. The PCR assay could detect as little as 10 fg of purified EDS-76 viral DNA. It also(More)
A series of new 1,2,3-triazolyl methyl ester of morpholine-3-carboxylic acid analogues were designed and synthesized employing click chemistry by using Huisgen 1,3 dipolar cyclo addition reaction between propargyl ester of morpholine-3-carboxylic acid and aryl azides. The starting materials propargyl ester and aryl azides were synthesized by well(More)
The data available on the distribution of variants, phenotype and gene frequencies of different placental isoenzymes, especially for caste populations of Andhra Pradesh, are very scanty. In the present study, phenotype and gene frequency distributions of placental alkaline phosphatase (PLAP) of two caste groups namely, Lambada and Perika of Andhra Pradesh,(More)
Three-hundred and thirty placental samples from two caste populations of Andhra Pradesh, South India, were screened by electrophoresis for the variants of acid phosphatase and for the phenotypes of alkaline phosphatase. Only the six common phenotypes of alkaline phosphatase were detected; no variants of acid phosphatase were found.
A series of novel sEH inhibitors containing a N-substituted piperidine ring [N-urea (8a–i) (9a–l) and amide derivatives (6a–l) (7a–l)] with pyrazole (a five-membered polar heterocycle) as a pharmacophore lead for sEH inhibition have been designed, synthesized and evaluated as novel analogues to reduce blood pressure elevation and inflammatory roles by(More)
The present paper gives the results of our study on the distribution of phenotypes and gene frequencies of placental alkaline phosphatase (PLAP) in the Shia and Khoja Muslim groups living in Hyderabad, Andhra Pradesh, South India. All six common PLAP phenotypes and three cases of rare phenotypes have been observed.
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