Nripendranath Mandal

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BACKGROUND The heartwood extract of A. catechu, called pale catechu or "Katha" in Hindi has been widely used in traditional Indian medicinal system. Although various pharmacological properties of this plant had been reported previously, only a few were concerned with the anticancer activity of this plant. OBJECTIVE The objective was to assess the in vitro(More)
BACKGROUND Cellular damage caused by reactive oxygen species (ROS) has been implicated in several diseases, and hence natural antioxidants have significant importance in human health. The present study was carried out to evaluate the in vitro antioxidant and reactive oxygen species scavenging activities of Terminalia chebula, Terminalia belerica and Emblica(More)
BACKGROUND Many diseases are associated with oxidative stress caused by free radicals. Current research is directed towards finding naturally-occurring antioxidants of plant origin. The aim of the present study was to evaluate the in vitro antioxidant activities of Spondias pinnata stem bark extract. METHODS A 70% methanol extract of Spondias pinnata stem(More)
The study aimed to analyse the global research output related to microRNA (miRNA), based on the fact that it has diverse expression patterns and might regulate various developmental and physiological processes. First miRNA was identified as small RNA in 1993 but its function as biological regulator was unknown till 2000. Since then the research in miRNAs(More)
The objective of the present study was to assess the in vitro anticancer activity of 70% methanolic extract of Terminalia belerica (TBME) against human lung (A549) and human breast (MCF-7) carcinoma and its possible mechanism. TBME showed significant cytotoxicity to both A549 and MCF-7 cells, whereas, no cytotoxicity was found in non-malignant WI-38 cells.(More)
"Oxidative stress" is initiated by reactive oxygen species (ROS), which are responsible for majority of the diseases. However, antioxidants with ROS scavenging ability may have great relevance in the prevention of oxidative stress. The present study was undertaken, using a 70% methanolic extract of Caesalpinia crista leaves, to examine different in vitro(More)
Shrimp aquaculture constitutes a major economic activity of some middle- and low-level economies in the world. Though it is practiced by around 70 countries, it is primarily dominated by China, Thailand, Indonesia, Vietnam, Ecuador and India. These six countries account for 80 % of the global shrimp production. The study has highlighted the role of research(More)
This report highlights the phytochemical analysis, antioxidant potential and anticancer activity against breast carcinoma of 70% methanolic extract of lichen, Parmotrema reticulatum (PRME). Phytochemical analysis of PRME confirms the presence of various phytoconstituents like alkaloids, carbohydrates, flavonoids, glycosides, phenols, saponins, tannins,(More)
BACKGROUND Spondias pinnata has been reported for its efficient anticancer effects, but the studies were mostly focused on its extract. OBJECTIVE Since its bioactive compounds are largely unknown, this study was designed to characterize the lead components present in it and their anticancer activity against human glioblastoma cell line (U87). MATERIALS(More)
BACKGROUND/AIMS Acute myocardial infarction (AMI) is a leading cause of death. Inflammatory processes play an important role in atherosclerosis, which is intimately related to AMI. The aim of this study was to investigate the association between anti-inflammatory and pro-inflammatory cytokines ratios and AMI. METHODS A total of 90 AMI patients and 90(More)