Nour-al-dain Marzouka

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UNLABELLED The Illumina Infinium HumanMethylation450 BeadChip (450k) is widely used for the evaluation of DNA methylation levels in large-scale datasets, particularly in cancer. The 450k design allows copy number variant (CNV) calling using existing bioinformatics tools. However, in cancer samples, numerous large-scale aberrations cause shifting in the(More)
A macular degeneration (AMD) is a late-onset disorder that affects the posterior part of the retina, the macula. The AMD is the most common cause of permanent elderly-blindness, and is a complex genetic disorder, in which several genetic, behavioral, and environmental factors can affect the disease onset. Characterizing risk factors for AMD is of great(More)
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