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Antisense RNAs (asRNAs) pair to RNAs expressed from the complementary strand, and their functions are thought to depend on nucleotide overlap with genes on the opposite strand. There is little information on the roles and mechanisms of asRNAs. We show that a cis asRNA acts in trans, using a domain outside its target complementary sequence. SprA1 small(More)
We report a functional type I toxin-antitoxin (TA) module expressed by a human pathogen, Staphylococcus aureus. TA systems consist of stable toxins and labile antitoxins encoded within small genetic modules widespread in eubacteria and archaea. TA genes provide stress adaptation and protection against DNA loss or invasion. The genes encoding the SprA1 toxic(More)
Radiation-induced soft errors are major reliability concerns in advanced technology nodes. The de facto approach for evaluation of the soft error vulnerability is to perform a costly fault injection campaign. Due to the long residency of some errors in system states, the error has to be traced for even millions of cycles. However, only a very small portion(More)
Due to the stochastic switching behavior of the bit-cell in Spin Transfer Torque Magnetic Random Access Memory (STT-MRAM), an excessive write margin is required to guarantee an acceptable level of reliability and yield. This prevents the usage of STT-MRAM in fast memories such as L1 or L2 caches. The excessive write margin of STT-MRAM can be reduced to a(More)
Autophosphorylation of a soluble approximately 48-kDa derivative of the insulin receptor protein-tyrosine kinase occurs at multiple tyrosine residues (analogous to tyrosines 1158, 1162, and 1163 in the kinase homology region of the native receptor and tyrosines 1328 and 1334 in the carboxyl-terminal tail) and is accompanied by an increase in the specific(More)
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