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Electrophysiological and hemodynamic studies have suggested that structures in the vicinity of the anterior cingulate cortex are involved in performance monitoring, particularly in detection of errors. Bidirectional interactions between the frontomedian system involved in performance monitoring and the lateral prefrontal cortex as well as the orbitofrontal(More)
We investigated the interaction between object- and space-based attention by measuring activity in early visual cortex. After central cueing, when subjects directed attention to a spatially defined part of an object, activity in early visual areas was enhanced at corresponding retinotopic representations but also at representations of other locations(More)
The cortical integration of auditory and visual features is crucial for efficient object recognition. Previous studies have shown that audiovisual (AV) integration is affected by where and when auditory and visual features occur. However, because relatively little is known about the impact of what is integrated, we here investigated the impact of semantic(More)
Successful remembering involves both hindering irrelevant information from entering working memory (WM) and actively maintaining relevant information online. Using a voxelwise lesion-behavior brain mapping approach in stroke patients, we observed that lesions of the left basal ganglia render WM susceptible to irrelevant information. Lesions of the right(More)
We investigated working memory in patients with focal brain damage involving subregions of the prefrontal cortex (PFC). Lesions in the dorsal portion of lateral PFC or the ventromedial portion of orbital PFC did not impair performance in tasks that required maintenance and monitoring of object or spatial information. Larger lesions involving both ventral(More)
Blood oxygen level-dependent (BOLD) responses were measured in parts of primary visual cortex that represented unstimulated visual field regions at different distances from a stimulated central target location. The composition of the visual scene varied by the presence or absence of additional peripheral distracter stimuli. Bottom-up effects were assessed(More)
In the past years, claims of cognitive and attentional function of the cerebellum have first been raised but were later refuted. One reason for this controversy might be that attentional deficits only occur when specific cerebellar structures are affected. To further elucidate this matter and to determine which cerebellar regions might be involved in(More)
Attending a certain region in space enhances activity in visual areas retinotopically mapped to this region; stimuli presented in this region are preferentially processed. The zoom lens model of visual attention proposes that the attended region can be adjusted in size and predicts a tradeoff between its size and processing efficiency because of limited(More)
We assessed the interference by distracter letters on target discrimination as a function of the distance between incompatible distracters and target. The slope of the response time-distance function supports a Mexican hat pattern of attentional modulation in the visual field. We relate the results to our recent finding of neural activity suppression in(More)
By enhancing neural activity in respective retinotopic cortical representations attention increases the efficiency with which visual information at a selected location is processed. Behavioral data also suggest that information from the vicinity of the attended region is actively suppressed. In search for a physiological correlate of this 'spotlight's(More)