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BACKGROUND The use of systemic calcineurin inhibitors for the treatment of patients with psoriasis is limited by toxicity, particularly nephrotoxicity. ISA247, a novel inhibitor, was effective and well tolerated in a phase II study of patients with plaque psoriasis. Therefore its efficacy was assessed in this phase III study. METHODS 451 patients aged(More)
985 Correspondence melanoma: a case report and review of the literature. syndrome associated with immunotherapy for patients with melanoma. Gallo R, et al. Bullous eruption with circulating pemphigus-like antibodies following interferon-alpha therapy. A 40-year-old Caucasian female presented to the clinic with a history of hyperhidrosis of the palms and(More)
Disclaimer: As in the original guidelines, physicians should use their best clinical judgment when determining whether and how to apply treatment recommendations in the individualized care of patients. This document is not intended to replace the guidance found in the relevant Canadian product monographs or other official information available for the(More)
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