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- Matthias Ernst, Meri Najdovska, +13 authors Brendan J Jenkins
- The Journal of clinical investigation
- 2008
Deregulated activation of STAT3 is frequently associated with many human hematological and epithelial malignancies, including gastric cancer. While exaggerated STAT3 signaling facilitates an… (More)
- Hazel Tye, Catherine L. Kennedy, +13 authors Brendan J Jenkins
- Cancer cell
- 2012
Gastric cancer (GC) is associated with chronic inflammation; however, the molecular mechanisms promoting tumorigenesis remain ill defined. Using a GC mouse model driven by hyperactivation of the… (More)
- Prithi S. Bhathal, Norman R. Hughes, Zachary D. Goodman
- The American journal of surgical pathology
- 1996
The cell phenotype of so-called bile duct adenoma (BDA) was investigated immunohistochemically using monoclonal antibodies to two recently identified antigens (designated D10 and 1F6) extracted from… (More)
- Heike Varnholt, Jean-Nicolas Vauthey, +4 authors Gregory Y. Lauwers
- The American journal of surgical pathology
- 2003
We report a case of biliary adenofibroma in a 47-year-old woman, who presented with right upper quadrant pain for several months. Abdominal imaging revealed a 16-cm solid and cystic mass in the left… (More)
- Norman R. Hughes, Chawalit Pairojkul, Simon G Royce, Andrew D Clouston, Prithi S. Bhathal
- Journal of clinical pathology
- 2006
AIM
To compare cell phenotypes displayed by cholangiocarcinomas and adjacent bile duct lesions in patients from an area endemic in liver-fluke infestation and those with sporadic cholangiocarcinoma.… (More)
- Norman R. Hughes
- The Australian journal of experimental biology…
- 1972
- Norman R. Hughes, Zachary D. Goodman, Prithi S. Bhathal
- The American journal of surgical pathology
- 2010
The so-called bile duct adenoma and peribiliary glands are characterized by the expression of two foregut antigens (designated D10 and 1F6) and secretion of acid mucin. On account of this similarity… (More)
- Norman R. Hughes, Prithi S. Bhathal
- Journal of clinical pathology
- 1997
AIM
To investigate the phenotype of cells comprising diffuse and intestinal-type gastric cancers using monoclonal antibodies to two antigens. One antigen (designated D10) is characteristic of gastric… (More)
- Norman R. Hughes, Ronald S. Walls, Ronald C. Newland, J E Payne
- Cancer research
- 1986
Monoclonal antibodies to normal colonic glands were used to localize three tissue-specific antigens in sections of 40 hyperplastic polyps, 29 adenomas, 43 colorectal adenocarcinomas, and blocks or… (More)
- Norman R. Hughes, Prithi S. Bhathal, David M. A. Francis
- Journal of clinical pathology
- 1994
AIM
To investigate the tissue specificity of a novel monoclonal antibody raised to a tissue fraction of normal human liver and which identified certain cells of gastric and duodenal mucosa.
METHODS… (More)