An attenuated chikungunya (CHIK) virus clone was developed for production of a live vaccine for human use. CHIK strain 15561 was subjected to 18 plaque-to-plaque passages in MRC-5 cultures before… (More)

Given a characteristic class on a locally ordered combinatorial manifold M there exists a cocycle which represents the class on M and is locally defined, i.e. its value on o E M depends only on the… (More)

The first author in [L] introduced the notion of "Poincaré transversality" for an iV-dimensional spherical fiber space, n : Ç -> X. If T(Ç) is the Thorn space of <f, then we consider T(Ç) = M4 u… (More)

1. A Poincaré duality space (abbreviated P.D. space) of dimension n ^ 0 is a finite complex M with the following property. Let M be embedded in S, k large, and let Rhea, regular neighborhood; then… (More)

Fetal rhesus monkeys were inoculated intracerebrally with an attenuated strain of western equine encephalitis virus. All animals developed microcephaly. Twelve of sixteen monkeys developed ex vacuo… (More)

This paper introduces the notion of an intrinsic transversality structure on a Poincare duality space X". Such a space has an intrinsic transversality structure if the embedding of X" into its… (More)

Enterovirus receptors of live HeLa cells have been shown to reappear after inactivation by proteolytic enzymes, provided the cells are incubated at 37 C in a nutritionally adequate medium.… (More)