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— In this paper, the performances of the quasi-Newton BFGS algorithm, the NEWUOA derivative free optimization algorithm, the Covariance Matrix Adaptation Evolution Strategy (CMA-ES), the Differential Evolution (DE) algorithm and a Particle Swarm Optimization (PSO) algorithm are compared experimentally on benchmark functions reflecting important challenges(More)
In order to establish a subtractive procedure that makes it possible to enrich selectively phage displayed antibodies directed against proteins constituting a difference between two populations of cells, a competitive selection strategy utilising two solid phases was developed and tested. Antibodies recognising a defined difference between two otherwise(More)
The specificity of Si nuclease toward RNA-DNA hybrids as studied using isotopes of phosphorus-32 and phosphorus-33 ABSTRACT Hybrids were formed from Bacillus oereus DNA and ribosomal RNA. They were treated with various combinations of Sj nuclease and ribonuclease, and the molar ratios of the RNA and DNA moieties remaining in the treated hybrids were(More)
In this paper we present a static value range analysis of signals within function block diagrams developed with Matlab/Simulink. We analyse signals with respect to their data type and compute an approximation of the possible value range of each signal represented by a set of intervals. In addition the analysis reports potential problems within the model,(More)
— In this paper, the performances of the quasi-Newton BFGS algorithm , the NEWUOA derivative free optimizer, the Covariance Matrix Adaptation Evolution Strategy (CMA-ES), the Differential Evolution (DE) algorithm and Particle Swarm Optimizers (PSO) are compared experimentally on benchmark functions reflecting important challenges encountered in real-world(More)
— In this paper, the performances of the quasi-Newton BFGS algorithm , the NEWUOA derivative free optimizer, the Covariance Matrix Adaptation Evolution Strategy (CMA-ES), the Differential Evolution (DE) algorithm and Particle Swarm Optimizers (PSO) are compared experimentally on benchmark functions reflecting important challenges encountered in real-world(More)
A fast, efficient and economical method for purification of DNA from various sources by the use of silica particles packed in homemade bead columns is described. The method is a further development of the method devised by Carter and Milton (1), improved by the introduction of a column operated with a vacuum system. The method is highly suitable for(More)